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PREDICTION OF HYPOECHOIC LESIONS ON ULTRASOUND OF PROSTATE CANCER BASED ON PSA INTERVAL AND GLEASON GROUP

Main Authors: Ivan Mangunsong, Albert, Pramod, Sawkar Vijay, Safriadi, Ferry, Hernowo, Bethy S
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Indonesian Urological Association , 2021
Subjects:
Prostate Cancer
Ultrasonography
Hypoechoic Lesion
Online Access: http://juri.urologi.or.id/juri/article/view/676
http://juri.urologi.or.id/juri/article/view/676/459
ctrlnum article-676
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">PREDICTION OF HYPOECHOIC LESIONS ON ULTRASOUND OF PROSTATE CANCER BASED ON PSA INTERVAL AND GLEASON GROUP</title><creator>Ivan Mangunsong, Albert</creator><creator>Pramod, Sawkar Vijay</creator><creator>Safriadi, Ferry</creator><creator>Hernowo, Bethy S</creator><subject lang="en-US">Prostate Cancer</subject><subject lang="en-US">Ultrasonography</subject><subject lang="en-US">Hypoechoic Lesion</subject><description lang="en-US">Objective: To evaluate hypoechoic lesion in transrectal ultrasonography of prostate (TRUS-P) predictive value on prostate cancer based on PSA Interval and Gleason Group. Material &amp;amp; Methods: An observational analytic study with a cross-sectional design take place from January 2015 to December 2018 analyzing patients who had undergone TRUS-P Biopsy at Hasan Sadikin Hospital. Patients are divided into several subgroups according to different PSA levels. A p-value &amp;lt; 0.05 was considered statistically significant. PPV, NPV, and Youden&#x2019;s index were all indexes reflecting the performance of a diagnostic test. Results: There were 35 cases (49.3%) with a visible hypoechoic lesion in TRUS and 36 cases (41.7%) without a visible hypoechoic lesion. In our study, 23.9% of the patients with hypoechoic lesions were diagnosed with prostate cancer on TRUSP-Biopsy. The results of the analysis with Youden&#x2019;s index show that PSA at intervals of 10-20 is the best predictor of diagnostic values. Then we analyzed the overall detection rate based on PSA interval. Patients with PSA &amp;gt; 20 ng/ml, hypoechoic lesions were significantly associated with Gleason Group. Conclusion: We concluded in our study that the hypoechoic lesion in transurethral ultrasonography of prostate could improve the predictive efficacy for diagnosing prostate cancer. &amp;nbsp;</description><publisher lang="en-US">Indonesian Urological Association</publisher><date>2021-07-15</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://juri.urologi.or.id/juri/article/view/676</identifier><identifier>10.32421/juri.v28i2.676</identifier><source lang="en-US">Indonesian Journal of Urology; Vol 28 No 2 (2021); 129-134</source><source>2355-1402</source><source>0853-442X</source><source>10.32421/juri.v28i2</source><language>eng</language><relation>http://juri.urologi.or.id/juri/article/view/676/459</relation><recordID>article-676</recordID></dc>
language eng
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
Other
File:application/pdf
File
Journal:eJournal
author Ivan Mangunsong, Albert
Pramod, Sawkar Vijay
Safriadi, Ferry
Hernowo, Bethy S
title PREDICTION OF HYPOECHOIC LESIONS ON ULTRASOUND OF PROSTATE CANCER BASED ON PSA INTERVAL AND GLEASON GROUP
publisher Indonesian Urological Association
publishDate 2021
topic Prostate Cancer
Ultrasonography
Hypoechoic Lesion
url http://juri.urologi.or.id/juri/article/view/676
http://juri.urologi.or.id/juri/article/view/676/459
contents Objective: To evaluate hypoechoic lesion in transrectal ultrasonography of prostate (TRUS-P) predictive value on prostate cancer based on PSA Interval and Gleason Group. Material &amp; Methods: An observational analytic study with a cross-sectional design take place from January 2015 to December 2018 analyzing patients who had undergone TRUS-P Biopsy at Hasan Sadikin Hospital. Patients are divided into several subgroups according to different PSA levels. A p-value &lt; 0.05 was considered statistically significant. PPV, NPV, and Youden’s index were all indexes reflecting the performance of a diagnostic test. Results: There were 35 cases (49.3%) with a visible hypoechoic lesion in TRUS and 36 cases (41.7%) without a visible hypoechoic lesion. In our study, 23.9% of the patients with hypoechoic lesions were diagnosed with prostate cancer on TRUSP-Biopsy. The results of the analysis with Youden’s index show that PSA at intervals of 10-20 is the best predictor of diagnostic values. Then we analyzed the overall detection rate based on PSA interval. Patients with PSA &gt; 20 ng/ml, hypoechoic lesions were significantly associated with Gleason Group. Conclusion: We concluded in our study that the hypoechoic lesion in transurethral ultrasonography of prostate could improve the predictive efficacy for diagnosing prostate cancer. &nbsp;
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first_indexed 2022-01-01T17:45:07Z
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