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Relationship Between Shift Work and the Risk of Prostate Cancer: An Evidence Base Case Report

Main Authors: Suhadi, Irwan , Widyahening, Indah , Ilyas, Muhammad
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: ILUNI MKK FKUI , 2021
Subjects:
Shift work
Prostate cancer
Online Access: http://ijcom.org/index.php/ijcom/article/view/4
http://ijcom.org/index.php/ijcom/article/view/4/4
ctrlnum article-4
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">Relationship Between Shift Work and the Risk of Prostate Cancer: An Evidence Base Case Report</title><creator>Suhadi, Irwan </creator><creator>Widyahening, Indah </creator><creator>Ilyas, Muhammad </creator><subject lang="en-US">Shift work, Prostate cancer</subject><description lang="en-US">Prostate cancer has been associated with jobs that involve some degree of work at night. In 2007, the International Agency for Research on Cancer (IARC) concluded that shift work involving circadian disruption was probably carcinogenic in humans. Exposure to artificial LAN (Light at Night) suppresses pineal melatonin secretion and subsequently leads to an increase of sex hormones, which in turn could increase the susceptibility to hormone-dependent cancers. Disruption of the circadian rhythm regulated by several clock genes controlling apoptosis and cell proliferation, repeated phase shifting leading to internal desynchronisation and defects in the regulation of the circadian cell cycle, and also sleep deprivation alters immune function. In this case, the authors assessed the relationship between workers in a manufacture company who had worked shift work for 30 years and an increased risk of prostate cancer. This case takes evidence base from several journals that support this hypothesis while doing a critical appraisal to determine its validity and applicability.</description><publisher lang="en-US">ILUNI MKK FKUI</publisher><date>2021-07-09</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://ijcom.org/index.php/ijcom/article/view/4</identifier><identifier>10.53773/ijcom.v1i1.4.23-31</identifier><source lang="en-US">The Indonesian Journal of Community and Occupational Medicine; Vol. 1 No. 1 (2021): ijcom; 23-31</source><source>2798-723X</source><source>10.53773/ijcom.v1i1</source><language>eng</language><relation>http://ijcom.org/index.php/ijcom/article/view/4/4</relation><rights lang="en-US">Copyright (c) 2021 The Indonesian Journal of Community and Occupational Medicine</rights><recordID>article-4</recordID></dc>
language eng
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
Other
File:application/pdf
File
Journal:eJournal
author Suhadi, Irwan
Widyahening, Indah
Ilyas, Muhammad
title Relationship Between Shift Work and the Risk of Prostate Cancer: An Evidence Base Case Report
publisher ILUNI MKK FKUI
publishDate 2021
topic Shift work
Prostate cancer
url http://ijcom.org/index.php/ijcom/article/view/4
http://ijcom.org/index.php/ijcom/article/view/4/4
contents Prostate cancer has been associated with jobs that involve some degree of work at night. In 2007, the International Agency for Research on Cancer (IARC) concluded that shift work involving circadian disruption was probably carcinogenic in humans. Exposure to artificial LAN (Light at Night) suppresses pineal melatonin secretion and subsequently leads to an increase of sex hormones, which in turn could increase the susceptibility to hormone-dependent cancers. Disruption of the circadian rhythm regulated by several clock genes controlling apoptosis and cell proliferation, repeated phase shifting leading to internal desynchronisation and defects in the regulation of the circadian cell cycle, and also sleep deprivation alters immune function. In this case, the authors assessed the relationship between workers in a manufacture company who had worked shift work for 30 years and an increased risk of prostate cancer. This case takes evidence base from several journals that support this hypothesis while doing a critical appraisal to determine its validity and applicability.
id IOS16099.article-4
institution Ikatan Alumni Magister Kedokteran Kerja Fakultas Kedokteran Universitas Indonesia (ILUNI MKK FKUI)
institution_id 6512
institution_type library:public
library
library The Indonesian Journal of Community and Occupational Medicine (IJCOM)
library_id 4820
collection The Indonesian Journal of Community and Occupational Medicine (IJCOM)
repository_id 16099
city JAKARTA PUSAT
province DKI JAKARTA
repoId IOS16099
first_indexed 2021-10-05T01:58:15Z
last_indexed 2021-10-05T01:58:15Z
recordtype dc
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