Correlation between hyperbilirubinemia in term infants and developmental delay in 2-4 year-old children
| Main Authors: | Wilar, Rocky, Masloman, Nurhayati, Lestari, Hesti, Tjeng, William Stephenson |
|---|---|
| Format: | Article info application/pdf eArticle |
| Bahasa: | eng |
| Terbitan: |
Indonesian Pediatric Society
, 2010
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| Online Access: |
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813 https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813/660 |
| ctrlnum |
article-813 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">Correlation between hyperbilirubinemia in term infants and developmental delay in 2-4 year-old children</title><creator>Wilar, Rocky</creator><creator>Masloman, Nurhayati</creator><creator>Lestari, Hesti</creator><creator>Tjeng, William Stephenson</creator><description lang="en-US">Background Up to 50 percent of term newborns have clinical jaundice during the first week of life. Many infants with bilirubin encephalopathy were asymptomatic, but they show neurodevelopmental delay few years later. Toxic effect occurs if unbound unconjugated bilirubin penetrates blood brain barrier and causes neuronal death.Objective To investigate the relationship between moderate hyperbilirubinemia in tenn infants and developmental delay in 2- 4 year-old children.Methods A retrospective cohort study was performed usingmedical record of infants born between 2006-2007 in Division of Neonatology Prof. R.D. Kandoll General Hospital, Manado. Data from the medical record consisted of weeks of gestation, birth weight, Apgar scores, diagnosis of sepsis, congenital anomalies. Tenn infants with appropriate weight for gestational age were visited at their home to undergo developmental screening by Denver II and Vineland Social Maturity Scale test.Results Fifty one children enrolled in this study (26 children with hyperbilirubinemia and 25 without  hyperbilirubinemia) consisted of 27 boys and 24 girls. Most children were 24 - 29 months old (24/51). The results of Vineland Social Maturity Scale test showed 14 children had delayed social maturation (10 Mth history of  hyperbilirubinemia). Denver II screening found 11 children had delayed language skill (10 Mth history of hyperbilirubinemia), 1 child Mth hyperbilirubinemia had delayed fine motoric and language skill.Conclusions T here is a relationship between moderate hyperbilirubinemia in tenn infants and developmental delay in 2 - 4 year old children.</description><publisher lang="en-US">Indonesian Pediatric Society</publisher><date>2010-06-30</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813</identifier><identifier>10.14238/pi50.3.2010.154-8</identifier><source lang="en-US">Paediatrica Indonesiana; Vol 50 No 3 (2010): May 2010; 154-8</source><source>2338-476X</source><source>0030-9311</source><source>10.14238/pi50.3.2010</source><language>eng</language><relation>https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813/660</relation><recordID>article-813</recordID></dc>
|
| language |
eng |
| format |
Journal:Article Journal Other:info:eu-repo/semantics/publishedVersion Other File:application/pdf File Journal:eArticle |
| author |
Wilar, Rocky Masloman, Nurhayati Lestari, Hesti Tjeng, William Stephenson |
| title |
Correlation between hyperbilirubinemia in term infants and developmental delay in 2-4 year-old children |
| publisher |
Indonesian Pediatric Society |
| publishDate |
2010 |
| url |
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813 https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/813/660 |
| contents |
Background Up to 50 percent of term newborns have clinical jaundice during the first week of life. Many infants with bilirubin encephalopathy were asymptomatic, but they show neurodevelopmental delay few years later. Toxic effect occurs if unbound unconjugated bilirubin penetrates blood brain barrier and causes neuronal death.Objective To investigate the relationship between moderate hyperbilirubinemia in tenn infants and developmental delay in 2- 4 year-old children.Methods A retrospective cohort study was performed usingmedical record of infants born between 2006-2007 in Division of Neonatology Prof. R.D. Kandoll General Hospital, Manado. Data from the medical record consisted of weeks of gestation, birth weight, Apgar scores, diagnosis of sepsis, congenital anomalies. Tenn infants with appropriate weight for gestational age were visited at their home to undergo developmental screening by Denver II and Vineland Social Maturity Scale test.Results Fifty one children enrolled in this study (26 children with hyperbilirubinemia and 25 without hyperbilirubinemia) consisted of 27 boys and 24 girls. Most children were 24 - 29 months old (24/51). The results of Vineland Social Maturity Scale test showed 14 children had delayed social maturation (10 Mth history of hyperbilirubinemia). Denver II screening found 11 children had delayed language skill (10 Mth history of hyperbilirubinemia), 1 child Mth hyperbilirubinemia had delayed fine motoric and language skill.Conclusions T here is a relationship between moderate hyperbilirubinemia in tenn infants and developmental delay in 2 - 4 year old children. |
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IOS4351.article-813 |
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Ikatan Dokter Anak Indonesia (IDAI) |
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1183 |
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library:special library |
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Badan Penerbit IDAI |
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1030 |
| collection |
Paediatrica Indonesiana |
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4351 |
| subject_area |
Pediatric/Pediatrik Newborn Infant, Neonates/Perawatan Bayi Baru Lahir, Neonatal |
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JAKARTA PUSAT |
| province |
DKI JAKARTA |
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IOS4351 |
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2017-07-11T01:01:16Z |
| last_indexed |
2019-05-07T07:58:36Z |
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dc |
| _version_ |
1686120186643480576 |
| score |
17.199596 |