Batasan Prostate Specific Antigen (PSA) Pada Pasien Kanker Prostat Untuk Memprediksi Metastasis ke Tulang di Rumah Sakit Sardjito, Yogyakarta = Predicting Bone Metastasis in Prostate Cancer Patients: Value of Prostate Specific Antigen at Sardjito Hospital,Yogyakarta
| Main Author: | Ahmad Sulaiman Lubis |
|---|---|
| Format: | Book x, 15 hlm, 21 x 29 cm |
| Bahasa: | ind |
| Terbitan: |
Program Pendidikan Dokter Spesialis Urologi
, 2014
|
| Subjects: | |
| Online Access: |
http://perpustakaan.fk.ui.ac.id/new-opac/index.php?p=show_detail&id=19128 |
| ctrlnum |
slims-19128 |
|---|---|
| fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>Batasan Prostate Specific Antigen (PSA) Pada Pasien Kanker Prostat Untuk Memprediksi Metastasis ke Tulang di Rumah Sakit Sardjito, Yogyakarta = Predicting Bone Metastasis in Prostate Cancer Patients: Value of Prostate Specific Antigen at Sardjito Hospital,Yogyakarta</title><creator>Ahmad Sulaiman Lubis</creator><publisher>Program Pendidikan Dokter Spesialis Urologi</publisher><date>2014</date><language>ind</language><type>Book:Book</type><identifier>http://perpustakaan.fk.ui.ac.id/new-opac/index.php?p=show_detail&id=19128</identifier><identifier>T 14 431 FK</identifier><description>Tujuan: Mengetahui batasan nilai PSA untuk memprediksi adanya metastasistulang pada pasien kanker prostat di RS Sardjito.Metode: Penelitian retrospektif, dengan mengumpulkan rekam medis pasienkanker prostat telah dilakukan bone scintigraphy di RS Sardjito tahun 2006 -2011.Hasil: Dari 83 pasien kanker prostat yang telah dilakukan bone scintigraphy,terdapat 55 pasien (66%) mengalami metastasis tulang dan terdapat 28 pasien (34 %) yang tidak mengalami metastasis tulang. Dari 55 pasien yang mengalami metastasis tulang, terdapat 11 pasien (20 %) dengan PSA kurang dari 20 ng/mldan terdapat 44 pasien (80 %) yang memiliki PSA lebih dari 20 ng/ml. Cut-offpoint PSA 17.65 ng/ml memiliki sensitivitas terbesar yaitu 85.5% dan spesifisitas53.6%.Kesimpulan: Pemeriksaan bone scintigraphy dianjurkan pada pasien dengan PSA> 17.65 ng/ml, sedangkan pada pasien dengan PSA < 17.65 dianjurkan padapasien dengan gejala klinis nyeri tulang.Objective: Prostate cancer shows a strong predilection to spread to the bones,with bone metastases identified at autopsy in up to 90 % of patients dying fromprostate cancer. Serum prostate specific antigen (PSA) concentration has beenwidely applied as a biomarker to diagnose and monitor prostate cancer.Technetium-99m methylene diphosphate (Tc—99m MDP) whole body bonescintigraphy is currently a well-accepted diagnostic procedure for bone metastasisin malignancy. The aim of this study was to establish a useful serum PSA cut-offvalue to predict the presence of bone metastasis in men with prostate cancer. Material and Methods: Consecutive male patients diagnosed with prostate cancer were retrospectively analyzed. All of the subjects had received Tc-99mMDP whole body bone scintigraphy and had their serum PSA concentrationmeasured at Sardjito Hospital, Yogyakarta. The proper cut-off value wasestablished based on statistical analysis in order to predict the possibility of bonemetastasis among prostate cancer patients.Results: In total, 83 consecutive male patients with prostate cancer were enrolled,and 55 patients (66 %) were confirmed by scintigraphic findings to have bonemetastases. A serum PSA concentration of 17,65 ng/ml gave the best sensitivity(78,33 %) and specificity (65,21 %). The positive predictive value, negativepredictive value were 85,45 % and 53,57 %, respectively (p</description><coverage>Jakarta</coverage><type>Other:x, 15 hlm, 21 x 29 cm</type><subject>NONE</subject><image>http://perpustakaan.fk.ui.ac.id/new-opac/images/default/image.png</image><recordID>slims-19128</recordID></dc>
|
| language |
ind |
| format |
Book:Book Book Other:x, 15 hlm, 21 x 29 cm Other |
| author |
Ahmad Sulaiman Lubis |
| title |
Batasan Prostate Specific Antigen (PSA) Pada Pasien Kanker Prostat Untuk Memprediksi Metastasis ke Tulang di Rumah Sakit Sardjito, Yogyakarta = Predicting Bone Metastasis in Prostate Cancer Patients: Value of Prostate Specific Antigen at Sardjito Hospital,Yogyakarta |
| publisher |
Program Pendidikan Dokter Spesialis Urologi |
| publishDate |
2014 |
| topic |
NONE |
| url |
http://perpustakaan.fk.ui.ac.id/new-opac/index.php?p=show_detail&id=19128 |
| contents |
Tujuan: Mengetahui batasan nilai PSA untuk memprediksi adanya metastasistulang pada pasien kanker prostat di RS Sardjito.Metode: Penelitian retrospektif, dengan mengumpulkan rekam medis pasienkanker prostat telah dilakukan bone scintigraphy di RS Sardjito tahun 2006 -2011.Hasil: Dari 83 pasien kanker prostat yang telah dilakukan bone scintigraphy,terdapat 55 pasien (66%) mengalami metastasis tulang dan terdapat 28 pasien (34 %) yang tidak mengalami metastasis tulang. Dari 55 pasien yang mengalami metastasis tulang, terdapat 11 pasien (20 %) dengan PSA kurang dari 20 ng/mldan terdapat 44 pasien (80 %) yang memiliki PSA lebih dari 20 ng/ml. Cut-offpoint PSA 17.65 ng/ml memiliki sensitivitas terbesar yaitu 85.5% dan spesifisitas53.6%.Kesimpulan: Pemeriksaan bone scintigraphy dianjurkan pada pasien dengan PSA> 17.65 ng/ml, sedangkan pada pasien dengan PSA < 17.65 dianjurkan padapasien dengan gejala klinis nyeri tulang.Objective: Prostate cancer shows a strong predilection to spread to the bones,with bone metastases identified at autopsy in up to 90 % of patients dying fromprostate cancer. Serum prostate specific antigen (PSA) concentration has beenwidely applied as a biomarker to diagnose and monitor prostate cancer.Technetium-99m methylene diphosphate (Tc—99m MDP) whole body bonescintigraphy is currently a well-accepted diagnostic procedure for bone metastasisin malignancy. The aim of this study was to establish a useful serum PSA cut-offvalue to predict the presence of bone metastasis in men with prostate cancer. Material and Methods: Consecutive male patients diagnosed with prostate cancer were retrospectively analyzed. All of the subjects had received Tc-99mMDP whole body bone scintigraphy and had their serum PSA concentrationmeasured at Sardjito Hospital, Yogyakarta. The proper cut-off value wasestablished based on statistical analysis in order to predict the possibility of bonemetastasis among prostate cancer patients.Results: In total, 83 consecutive male patients with prostate cancer were enrolled,and 55 patients (66 %) were confirmed by scintigraphic findings to have bonemetastases. A serum PSA concentration of 17,65 ng/ml gave the best sensitivity(78,33 %) and specificity (65,21 %). The positive predictive value, negativepredictive value were 85,45 % and 53,57 %, respectively (p |
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Fakultas Kedokteran Universitas Indonesia |
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hellis.onesearch.id |
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2022-03-16T03:42:15Z |
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