STUDY OF THE INFLUENCE OF L-NORVALINE, ROSUVASTATIN AND THEIR COMBINATION ON THE LEVEL OF MICROCIRCULATION IN BONE TISSUE IN EXPERIMENTAL OSTEOPOROSIS AND FRACTURES ON ITS BACKGROUND

Main Authors: Densingh, Samuel, Gudyrev, Oleg, Faitelson, Alexander, Stepchenko, Aleksandr, Dolzhikov, Alexandr, Povetkin, Sergej
Format: Article
Terbitan: Pensoft Publishers , 2016
Subjects:
Online Access: https://zenodo.org/record/2534730
ctrlnum 2534730
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format Journal:Article
Journal
author Densingh, Samuel
Gudyrev, Oleg
Faitelson, Alexander
Stepchenko, Aleksandr
Dolzhikov, Alexandr
Povetkin, Sergej
title STUDY OF THE INFLUENCE OF L-NORVALINE, ROSUVASTATIN AND THEIR COMBINATION ON THE LEVEL OF MICROCIRCULATION IN BONE TISSUE IN EXPERIMENTAL OSTEOPOROSIS AND FRACTURES ON ITS BACKGROUND
publisher Pensoft Publishers
publishDate 2016
isbn 2313897120162
topic osteoporosis
osteoporotic fracture
microcirculation
endothelial dysfunction
L-norvaline
rosuvastatin
Bivalos
url https://zenodo.org/record/2534730
contents The experiment was carried out in female white Wistar rats to investigate the effect of L-norvaline, rosuvastatin and their combination on parameters of blood supply to the bone tissue on models of experimental osteoporosis and osteoporotic fractures. It was found that the studied drugs prevent reduction of microcirculation in osteoporotic bone tissue as well as in callus tissue of experimental osteoporotic fractures and it positively influences the course of reparative regeneration of bone tissue.
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