ABO Blood Group is Associated with COVID-19 Susceptibility: a Systematic Review
| Main Authors: | Richard Chinaza Ikeagwulonu, Chinonyelum Thecla Ezeonu, Mark Uchejeso Obeta, Ngozi Immaculata Ugwu, Nkereuwem Sunday Etukudoh, Henry Chukwuemeka Uro-Chukwu, Ifeyinwa Chizoba Akamike, Zeal Chinwe Ikeagwulonu |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2020
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4344131 |
| ctrlnum |
4344131 |
|---|---|
| fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Richard Chinaza Ikeagwulonu</creator><creator>Chinonyelum Thecla Ezeonu</creator><creator>Mark Uchejeso Obeta</creator><creator>Ngozi Immaculata Ugwu</creator><creator>Nkereuwem Sunday Etukudoh</creator><creator>Henry Chukwuemeka Uro-Chukwu</creator><creator>Ifeyinwa Chizoba Akamike</creator><creator>Zeal Chinwe Ikeagwulonu</creator><date>2020-12-17</date><description>Introduction: Conflicting evidences exist that ABO blood groups correlate with the susceptibility to COVID-19 and its clinical outcomes. This study aimed to pool available articles that assessed a possible relationship between COVID-19 and ABO blood groups.
Materials and methods: A search was conducted in four databases comprising Pubmed/Medline, Google scholar, Journal storage (JSTOR) and African Journals Online (AJOL) for relevant studies available before 25th August 2020 and contained extractable data on ABO blood type distribution and COVID-19 disease. Search terms included a combination of “ABO blood group, and COVID-19, coronavirus, and SARS-COV-2”.
Results: Fourteen articles that met study inclusion criteria were selected from a total of five hundred and eighty-five articles identified through database search. The fourteen articles reviewed comprised of a total of 73934 subjects (13189 SARS-COV-2 positive cases and 60745 controls). Overall, the risk of SARS-COV-2 infection was found to be significantly increased in patients with blood group A with ORs: 1.24 (95%Cl: 1.09-1.41, P = 0.001). Additionally, blood group O subjects were seen to have decreased odds of contracting COVID-19 infection (OR: 0.78, 95%Cl: 0.68 – 0.89, P=0.0003). No significant association was found between ABO blood groups and COVID -19 severity and mortality.
Conclusions: Blood group A was associated with a higher risk of SARS-COV-2 infection whereas risk of infection was lower in blood group O subjects. No statistical significant association was found between ABO blood groups and COVID-19 severity and mortality. The precise role of ABO blood group in COVID-19 susceptibility, severity and mortality requires further research for clarification.</description><identifier>https://zenodo.org/record/4344131</identifier><identifier>10.5281/zenodo.4344131</identifier><identifier>oai:zenodo.org:4344131</identifier><language>eng</language><relation>doi:10.5281/zenodo.4344130</relation><relation>url:https://zenodo.org/communities/iberoamjmed</relation><rights>info:eu-repo/semantics/openAccess</rights><rights>https://creativecommons.org/licenses/by/4.0/legalcode</rights><source>Iberoamerican Journal of Medicine 3(1) 71-84</source><subject>ABO blood group</subject><subject>Susceptibility</subject><subject>Severity</subject><subject>Mortality</subject><subject>COVID-19</subject><subject>SARS-COV-2</subject><title>ABO Blood Group is Associated with COVID-19 Susceptibility: a Systematic Review</title><type>Journal:Article</type><type>Journal:Article</type><recordID>4344131</recordID></dc>
|
| language |
eng |
| format |
Journal:Article Journal Journal:Journal |
| author |
Richard Chinaza Ikeagwulonu Chinonyelum Thecla Ezeonu Mark Uchejeso Obeta Ngozi Immaculata Ugwu Nkereuwem Sunday Etukudoh Henry Chukwuemeka Uro-Chukwu Ifeyinwa Chizoba Akamike Zeal Chinwe Ikeagwulonu |
| title |
ABO Blood Group is Associated with COVID-19 Susceptibility: a Systematic Review |
| publishDate |
2020 |
| topic |
ABO blood group Susceptibility Severity Mortality COVID-19 SARS-COV-2 |
| url |
https://zenodo.org/record/4344131 |
| contents |
Introduction: Conflicting evidences exist that ABO blood groups correlate with the susceptibility to COVID-19 and its clinical outcomes. This study aimed to pool available articles that assessed a possible relationship between COVID-19 and ABO blood groups.
Materials and methods: A search was conducted in four databases comprising Pubmed/Medline, Google scholar, Journal storage (JSTOR) and African Journals Online (AJOL) for relevant studies available before 25th August 2020 and contained extractable data on ABO blood type distribution and COVID-19 disease. Search terms included a combination of “ABO blood group, and COVID-19, coronavirus, and SARS-COV-2”.
Results: Fourteen articles that met study inclusion criteria were selected from a total of five hundred and eighty-five articles identified through database search. The fourteen articles reviewed comprised of a total of 73934 subjects (13189 SARS-COV-2 positive cases and 60745 controls). Overall, the risk of SARS-COV-2 infection was found to be significantly increased in patients with blood group A with ORs: 1.24 (95%Cl: 1.09-1.41, P = 0.001). Additionally, blood group O subjects were seen to have decreased odds of contracting COVID-19 infection (OR: 0.78, 95%Cl: 0.68 – 0.89, P=0.0003). No significant association was found between ABO blood groups and COVID -19 severity and mortality.
Conclusions: Blood group A was associated with a higher risk of SARS-COV-2 infection whereas risk of infection was lower in blood group O subjects. No statistical significant association was found between ABO blood groups and COVID-19 severity and mortality. The precise role of ABO blood group in COVID-19 susceptibility, severity and mortality requires further research for clarification. |
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IOS16997.4344131 |
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ZAIN Publications |
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7213 |
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library:special library |
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Cognizance Journal of Multidisciplinary Studies |
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Cognizance Journal of Multidisciplinary Studies |
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16997 |
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Multidisciplinary |
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Stockholm |
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INTERNASIONAL |
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1 |
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2022-06-06T05:17:12Z |
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