Recurrence of glioblastoma multiforme in a childhood: A case report

Main Authors: Fahimma, Yuyun Yueniwati, Dessika Rahmawati, Fany Cahyawati
Format: Article Journal
Bahasa: eng
Terbitan: , 2020
Subjects:
Online Access: https://zenodo.org/record/4421483
ctrlnum 4421483
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Fahimma</creator><creator>Yuyun Yueniwati</creator><creator>Dessika Rahmawati</creator><creator>Fany Cahyawati</creator><date>2020-12-30</date><description>GBM is a highly aggressive malignant tumor that rarely happens in children. Pediatric GBM is the primary cause of death in children with brain neoplasms. Treatment of GBM is a difficult and challenging condition, especially in pediatric GBM. Surgical tumor resection combined with chemoradiotherapy suggests as standard therapeutic approaches for GBM. However, the recurrence of GBM is an inevitable event and can occur in more than 90% of patients. We present an unusual case of an 11-years-old girl with recurrence of GBM. She complained of progressive headache and left hemiparesis as an initial manifestation. She was diagnosed with GBM three years before. Near-total surgical resection followed with chemotherapy, and radiotherapy was done after the diagnosis. Head imaging showed a smaller lesion, and her symptoms were improved significantly. Two years after, she was admitted to the hospital with worsening symptoms. Imaging evaluation showed the enlargement of tumor lesions. Recurrence of GBM is a great challenge to manage, and there are no well-defined management protocols. Several studies suggest that treatment options may follow the adult patients' approach, but pediatric GBM has significantly different characteristics than adults. </description><identifier>https://zenodo.org/record/4421483</identifier><identifier>10.5281/zenodo.4421483</identifier><identifier>oai:zenodo.org:4421483</identifier><language>eng</language><relation>info:eu-repo/semantics/altIdentifier/doi/10.30574/wjarr.2020.8.3.0488</relation><relation>doi:10.5281/zenodo.4421482</relation><relation>url:https://zenodo.org/communities/wjarr</relation><rights>info:eu-repo/semantics/openAccess</rights><rights>https://creativecommons.org/licenses/by/4.0/legalcode</rights><source>World Journal of Advanced Research and Reviews 8(3) 407-412</source><subject>Glioblastoma Multiforme; Recurrence; Pediatric; Childhood</subject><title>Recurrence of glioblastoma multiforme in a childhood: A case report</title><type>Journal:Article</type><type>Journal:Article</type><recordID>4421483</recordID></dc>
language eng
format Journal:Article
Journal
Journal:Journal
author Fahimma
Yuyun Yueniwati
Dessika Rahmawati
Fany Cahyawati
title Recurrence of glioblastoma multiforme in a childhood: A case report
publishDate 2020
topic Glioblastoma Multiforme
Recurrence
Pediatric
Childhood
url https://zenodo.org/record/4421483
contents GBM is a highly aggressive malignant tumor that rarely happens in children. Pediatric GBM is the primary cause of death in children with brain neoplasms. Treatment of GBM is a difficult and challenging condition, especially in pediatric GBM. Surgical tumor resection combined with chemoradiotherapy suggests as standard therapeutic approaches for GBM. However, the recurrence of GBM is an inevitable event and can occur in more than 90% of patients. We present an unusual case of an 11-years-old girl with recurrence of GBM. She complained of progressive headache and left hemiparesis as an initial manifestation. She was diagnosed with GBM three years before. Near-total surgical resection followed with chemotherapy, and radiotherapy was done after the diagnosis. Head imaging showed a smaller lesion, and her symptoms were improved significantly. Two years after, she was admitted to the hospital with worsening symptoms. Imaging evaluation showed the enlargement of tumor lesions. Recurrence of GBM is a great challenge to manage, and there are no well-defined management protocols. Several studies suggest that treatment options may follow the adult patients' approach, but pediatric GBM has significantly different characteristics than adults.
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library Cognizance Journal of Multidisciplinary Studies
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collection Cognizance Journal of Multidisciplinary Studies
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subject_area Multidisciplinary
city Stockholm
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