Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study
Main Authors: | Satarupa Bhattacherjee, Munmun Bardhan, Aniruddha Banerjee, Madhureema Dey, Ruma Basu, Sukhen Das, Sandip Kumar Sinha |
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Format: | Article Journal |
Bahasa: | ang |
Terbitan: |
, 2022
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Online Access: |
https://zenodo.org/record/6343239 |
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6343239 |
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fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Satarupa Bhattacherjee</creator><creator>Munmun Bardhan</creator><creator>Aniruddha Banerjee</creator><creator>Madhureema Dey</creator><creator>Ruma Basu</creator><creator>Sukhen Das</creator><creator>Sandip Kumar Sinha</creator><date>2022-03-10</date><description>Green synthesized manganese oxide (MnO2) nano-conjugate have been widely used as biomedicine in different medical applications. Solanum lycopersicum (Tomato) extract is used to synthesizes MnO2 nanoparticles following a green route, and the synthesized nanoparticles is characterized by XRD, FTIR, UV-Vis, SEM, and later on applied for the evaluation of hepato-protective and anti-oxidant activities in mice. Biochemical tests such as bilirubin, liver function test (LFT), hematological parameters provide evidences for high and non-toxic efficacy of green synthesized nanomaterials in the symptomatic treatment of hepatic damage. Histopathological changes in liver were investigated in presence of the synthesized nanoconjugate and compared with conventional drug. These results suggest that these green synthesized nanomaterials could appear as an important ameliorative agent and effective for jaundice as well as other related hepatic disorders and could be developed as safe and efficient alternatives to conventional drugs.</description><identifier>https://zenodo.org/record/6343239</identifier><identifier>10.5281/zenodo.6343239</identifier><identifier>oai:zenodo.org:6343239</identifier><language>ang</language><relation>doi:10.5281/zenodo.6343238</relation><rights>info:eu-repo/semantics/openAccess</rights><rights>https://creativecommons.org/licenses/by/4.0/legalcode</rights><source>International Journal Of Pharmaceutical And Bio-Medical Science 02(03) 33-42</source><subject>Solanum lycopersicum, Green Synthesis, Nanoparticle, Jaundice, Total Bilirubin, LFT.</subject><title>Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study</title><type>Journal:Article</type><type>Journal:Article</type><recordID>6343239</recordID></dc>
|
language |
ang |
format |
Journal:Article Journal Journal:Journal |
author |
Satarupa Bhattacherjee Munmun Bardhan Aniruddha Banerjee Madhureema Dey Ruma Basu Sukhen Das Sandip Kumar Sinha |
title |
Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study |
publishDate |
2022 |
topic |
Solanum lycopersicum Green Synthesis Nanoparticle Jaundice Total Bilirubin LFT |
url |
https://zenodo.org/record/6343239 |
contents |
Green synthesized manganese oxide (MnO2) nano-conjugate have been widely used as biomedicine in different medical applications. Solanum lycopersicum (Tomato) extract is used to synthesizes MnO2 nanoparticles following a green route, and the synthesized nanoparticles is characterized by XRD, FTIR, UV-Vis, SEM, and later on applied for the evaluation of hepato-protective and anti-oxidant activities in mice. Biochemical tests such as bilirubin, liver function test (LFT), hematological parameters provide evidences for high and non-toxic efficacy of green synthesized nanomaterials in the symptomatic treatment of hepatic damage. Histopathological changes in liver were investigated in presence of the synthesized nanoconjugate and compared with conventional drug. These results suggest that these green synthesized nanomaterials could appear as an important ameliorative agent and effective for jaundice as well as other related hepatic disorders and could be developed as safe and efficient alternatives to conventional drugs. |
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IOS16997.6343239 |
institution |
ZAIN Publications |
institution_id |
7213 |
institution_type |
library:special library |
library |
Cognizance Journal of Multidisciplinary Studies |
library_id |
5267 |
collection |
Cognizance Journal of Multidisciplinary Studies |
repository_id |
16997 |
subject_area |
Multidisciplinary |
city |
Stockholm |
province |
INTERNASIONAL |
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1 |
repoId |
IOS16997 |
first_indexed |
2022-06-06T04:08:47Z |
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2022-06-06T04:08:47Z |
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1734901118738104320 |
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17.610544 |