Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study

Main Authors: Satarupa Bhattacherjee, Munmun Bardhan, Aniruddha Banerjee, Madhureema Dey, Ruma Basu, Sukhen Das, Sandip Kumar Sinha
Format: Article Journal
Bahasa: ang
Terbitan: , 2022
Subjects:
LFT
Online Access: https://zenodo.org/record/6343239
ctrlnum 6343239
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Satarupa Bhattacherjee</creator><creator>Munmun Bardhan</creator><creator>Aniruddha Banerjee</creator><creator>Madhureema Dey</creator><creator>Ruma Basu</creator><creator>Sukhen Das</creator><creator>Sandip Kumar Sinha</creator><date>2022-03-10</date><description>Green synthesized manganese oxide (MnO2) nano-conjugate have been widely used as biomedicine in different medical applications. Solanum lycopersicum (Tomato) extract is used to synthesizes MnO2 nanoparticles following a green route, and the synthesized nanoparticles is characterized by XRD, FTIR, UV-Vis, SEM, and later on applied for the evaluation of hepato-protective and anti-oxidant activities in mice. Biochemical tests such as bilirubin, liver function test (LFT), hematological parameters provide evidences for high and non-toxic efficacy of green synthesized nanomaterials in the symptomatic treatment of hepatic damage. Histopathological changes in liver were investigated in presence of the synthesized nanoconjugate and compared with conventional drug. These results suggest that these green synthesized nanomaterials could appear as an important ameliorative agent and effective for jaundice as well as other related hepatic disorders and could be developed as safe and efficient alternatives to conventional drugs.</description><identifier>https://zenodo.org/record/6343239</identifier><identifier>10.5281/zenodo.6343239</identifier><identifier>oai:zenodo.org:6343239</identifier><language>ang</language><relation>doi:10.5281/zenodo.6343238</relation><rights>info:eu-repo/semantics/openAccess</rights><rights>https://creativecommons.org/licenses/by/4.0/legalcode</rights><source>International Journal Of Pharmaceutical And Bio-Medical Science 02(03) 33-42</source><subject>Solanum lycopersicum, Green Synthesis, Nanoparticle, Jaundice, Total Bilirubin, LFT.</subject><title>Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study</title><type>Journal:Article</type><type>Journal:Article</type><recordID>6343239</recordID></dc>
language ang
format Journal:Article
Journal
Journal:Journal
author Satarupa Bhattacherjee
Munmun Bardhan
Aniruddha Banerjee
Madhureema Dey
Ruma Basu
Sukhen Das
Sandip Kumar Sinha
title Therapeutic effect of Green synthesized MnO2 nanoparticles for treatment of hyperbilirubinemia -An In-Vivo Study
publishDate 2022
topic Solanum lycopersicum
Green Synthesis
Nanoparticle
Jaundice
Total Bilirubin
LFT
url https://zenodo.org/record/6343239
contents Green synthesized manganese oxide (MnO2) nano-conjugate have been widely used as biomedicine in different medical applications. Solanum lycopersicum (Tomato) extract is used to synthesizes MnO2 nanoparticles following a green route, and the synthesized nanoparticles is characterized by XRD, FTIR, UV-Vis, SEM, and later on applied for the evaluation of hepato-protective and anti-oxidant activities in mice. Biochemical tests such as bilirubin, liver function test (LFT), hematological parameters provide evidences for high and non-toxic efficacy of green synthesized nanomaterials in the symptomatic treatment of hepatic damage. Histopathological changes in liver were investigated in presence of the synthesized nanoconjugate and compared with conventional drug. These results suggest that these green synthesized nanomaterials could appear as an important ameliorative agent and effective for jaundice as well as other related hepatic disorders and could be developed as safe and efficient alternatives to conventional drugs.
id IOS16997.6343239
institution ZAIN Publications
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library Cognizance Journal of Multidisciplinary Studies
library_id 5267
collection Cognizance Journal of Multidisciplinary Studies
repository_id 16997
subject_area Multidisciplinary
city Stockholm
province INTERNASIONAL
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repoId IOS16997
first_indexed 2022-06-06T04:08:47Z
last_indexed 2022-06-06T04:08:47Z
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