A NEW STOCHASTIC MODEL TO ESTIMATE THE INFLUENCE OF INSULIN ON CIRCULATING GHRELIN USING GAMMA DISTRIBUTION
| Main Authors: | Dr. P. Senthil Kumar, K. Balasubramanian, A. Dinesh Kumar |
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| Format: | Article eJournal |
| Terbitan: |
, 2016
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/154741 |
Daftar Isi:
- Ghrelin is a novel peptide that acts on the growth hormone (GH) secretagogue receptor in the pituitary and hypothalamus. It may functions as a third physiological regulator of GH secretion, along with GH-releasing hormone and somatostatin. In addition to the action of ghrelin on the GH axis, it appears to have a role in the determination of energy homeostasis. Although feeding suppresses ghrelin production and fasting stimulates ghrelin release, the underlying mechanisms controlling this process remain unclear. Our data suggest that insulin may suppress circulating ghrelin independently of glucose, although glucose may have an additional effect. The purpose of this study was to estimate the influence of insulin on circulating ghrelin using gamma distribution with the help of duality principle.