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ENDOTHELIUM AND CARDIOPROTECTIVE EFFECTS OF HMG-CO-A-REDUCTASE IN COMBINATION WITH L-ARGININE IN ENDOTHELIAL DYSFUNCTION MODELING

Main Authors: Denisyuk, Tatiana, Lazareva, Galina, Provotorov, Vladimir, Pokrovskaya, Tatyana
Format: Article eJournal
Terbitan: Pensoft Publishers , 2016
Subjects:
endothelial dysfunction
HMG-Co-A reductase inhibitor simvastatin
atorvastatin
rosuvastatin
endotoxin
Online Access: https://zenodo.org/record/2534724
ctrlnum 2534724
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Denisyuk, Tatiana</creator><creator>Lazareva, Galina</creator><creator>Provotorov, Vladimir</creator><creator>Pokrovskaya, Tatyana</creator><date>2016-03-30</date><description>Using the combined application of L-arginine with HMG-Co-A reductase inhibitors simvastatin, atorvastatin, rosuvastatin and nanoparticulated rosuvastatin on the background of modeling of sepsis-induced disease through the introduction of strain 603 Staphylococcus aureus shows endotelio- and cardioprotective effects, manifesting itself in preventing the proliferation of endothelial dysfunction coefficient (CED), adrenoreactivity, maintenance of myocardial reserve and the normalization of biochemical markers values (Total NO, eNOS expression, C-reactive protein, IL-6, TNF). In this case, the combined therapy was so effective that the values obtained thereunder did not differ from those obtained from control animals.</description><identifier>https://zenodo.org/record/2534724</identifier><identifier>10.18413/2313-8971-2016-2-1-4-8</identifier><identifier>oai:zenodo.org:2534724</identifier><publisher>Pensoft Publishers</publisher><rights>info:eu-repo/semantics/openAccess</rights><rights>https://creativecommons.org/licenses/by/4.0/legalcode</rights><source>Research Results in Pharmacology 2((1)) 4-8</source><subject>endothelial dysfunction</subject><subject>HMG-Co-A reductase inhibitor simvastatin</subject><subject>atorvastatin</subject><subject>rosuvastatin</subject><subject>endotoxin.</subject><title>ENDOTHELIUM AND CARDIOPROTECTIVE EFFECTS OF HMG-CO-A-REDUCTASE IN COMBINATION WITH L-ARGININE IN ENDOTHELIAL DYSFUNCTION MODELING</title><type>Journal:Article</type><type>Journal:Article</type><recordID>2534724</recordID></dc>
format Journal:Article
Journal
Journal:eJournal
author Denisyuk, Tatiana
Lazareva, Galina
Provotorov, Vladimir
Pokrovskaya, Tatyana
title ENDOTHELIUM AND CARDIOPROTECTIVE EFFECTS OF HMG-CO-A-REDUCTASE IN COMBINATION WITH L-ARGININE IN ENDOTHELIAL DYSFUNCTION MODELING
publisher Pensoft Publishers
publishDate 2016
isbn 2313897120162
topic endothelial dysfunction
HMG-Co-A reductase inhibitor simvastatin
atorvastatin
rosuvastatin
endotoxin
url https://zenodo.org/record/2534724
contents Using the combined application of L-arginine with HMG-Co-A reductase inhibitors simvastatin, atorvastatin, rosuvastatin and nanoparticulated rosuvastatin on the background of modeling of sepsis-induced disease through the introduction of strain 603 Staphylococcus aureus shows endotelio- and cardioprotective effects, manifesting itself in preventing the proliferation of endothelial dysfunction coefficient (CED), adrenoreactivity, maintenance of myocardial reserve and the normalization of biochemical markers values (Total NO, eNOS expression, C-reactive protein, IL-6, TNF). In this case, the combined therapy was so effective that the values obtained thereunder did not differ from those obtained from control animals.
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institution Universitas PGRI Palembang
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collection Marga Life in South Sumatra in the Past: Puyang Concept Sacrificed and Demythosized
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city KOTA PALEMBANG
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last_indexed 2022-07-26T03:11:09Z
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