Tampilan Petugas: Dataset related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis"

Dataset related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis"

Main Authors:	Navarria, Pierina, Pessina, Federico, Franzese, Ciro, Tomatis, Stefano Maria, Perrino, Matteo Romualdo Anania, Cozzi, Luca, Simonelli, Matteo, Bello, Lorenzo, Clerici, Elena, Riva, Marco, Santoro, Armando, Scorsetti, Marta
Format:	info dataset eJournal
Terbitan:	, 2019
Subjects:	Glioblastoma Propensity score matching Radiation therapy
Online Access:	https://zenodo.org/record/3517909

ctrlnum	3517909
fullrecord	<?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><creator>Navarria, Pierina</creator><creator>Pessina, Federico</creator><creator>Franzese, Ciro</creator><creator>Tomatis, Stefano Maria</creator><creator>Perrino, Matteo Romualdo Anania</creator><creator>Cozzi, Luca</creator><creator>Simonelli, Matteo</creator><creator>Bello, Lorenzo</creator><creator>Clerici, Elena</creator><creator>Riva, Marco</creator><creator>Santoro, Armando</creator><creator>Scorsetti, Marta</creator><date>2019-09-13</date><description>This record contains raw data related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis" The current treatment for newly diagnosed glioblastoma consists of surgery followed by conventional radiotherapy (CRT) with concomitant and adjuvant chemotherapy. Hypofractionated radiation therapy (HFRT) has been investigated and it resulted feasible and safe. The aim of this study was to evaluate whether HFRT can be comparable to CRT. MATERIALS AND METHODS: The analysis included newly diagnosed glioblastoma patients treated with CRT 60 Gy/30 fractions or HFRT 60 Gy/15 fractions. A propensity score matching analysis (PSM) was performed using a logistic regression that considered age, KPS, extent of surgery, MGMT and IDH status. RESULTS: A total of 267 patients were included; before PSM 169 were in CRT-group and 98 in HRFT-group. After 1:1 matching, 82 patients resulted in each group. The median OS time was 17.9 months for the CRT-group and 16.7 months for the HFRT-group; the 1, 2, 3-year OS rates were 75.6%, 32.7%, and 15.5% for the CRT-group, and 75.6%, 33.3%, and 18.9% for the HFRT-group (p value = 0.8). No statistically significant differences were recorded between the two radiation therapy treatments performed. CONCLUSIONS: A short course of radiation therapy would seem comparable to CRT in terms of outcome and less burdensome for these poor prognosis patients. </description><identifier>https://zenodo.org/record/3517909</identifier><identifier>10.5281/zenodo.3517909</identifier><identifier>oai:zenodo.org:3517909</identifier><relation>doi:10.1016/j.radonc.2017.12.006</relation><relation>pmid:29291951</relation><relation>doi:10.5281/zenodo.3407388</relation><relation>url:https://zenodo.org/communities/humanitasirccs</relation><rights>info:eu-repo/semantics/restrictedAccess</rights><subject>Glioblastoma</subject><subject>Propensity score matching</subject><subject>Radiation therapy</subject><title>Dataset related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis"</title><type>Other:info:eu-repo/semantics/other</type><type>Other:dataset</type><recordID>3517909</recordID></dc>
format	Other:info:eu-repo/semantics/other Other Other:dataset Journal:eJournal Journal
author	Navarria, Pierina Pessina, Federico Franzese, Ciro Tomatis, Stefano Maria Perrino, Matteo Romualdo Anania Cozzi, Luca Simonelli, Matteo Bello, Lorenzo Clerici, Elena Riva, Marco Santoro, Armando Scorsetti, Marta
title	Dataset related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis"
publishDate	2019
topic	Glioblastoma Propensity score matching Radiation therapy
url	https://zenodo.org/record/3517909
contents	This record contains raw data related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis" The current treatment for newly diagnosed glioblastoma consists of surgery followed by conventional radiotherapy (CRT) with concomitant and adjuvant chemotherapy. Hypofractionated radiation therapy (HFRT) has been investigated and it resulted feasible and safe. The aim of this study was to evaluate whether HFRT can be comparable to CRT. MATERIALS AND METHODS: The analysis included newly diagnosed glioblastoma patients treated with CRT 60 Gy/30 fractions or HFRT 60 Gy/15 fractions. A propensity score matching analysis (PSM) was performed using a logistic regression that considered age, KPS, extent of surgery, MGMT and IDH status. RESULTS: A total of 267 patients were included; before PSM 169 were in CRT-group and 98 in HRFT-group. After 1:1 matching, 82 patients resulted in each group. The median OS time was 17.9 months for the CRT-group and 16.7 months for the HFRT-group; the 1, 2, 3-year OS rates were 75.6%, 32.7%, and 15.5% for the CRT-group, and 75.6%, 33.3%, and 18.9% for the HFRT-group (p value = 0.8). No statistically significant differences were recorded between the two radiation therapy treatments performed. CONCLUSIONS: A short course of radiation therapy would seem comparable to CRT in terms of outcome and less burdensome for these poor prognosis patients.
id	IOS17403.3517909
institution	Universitas PGRI Palembang
institution_id	189
institution_type	library:university library
library	Perpustakaan Universitas PGRI Palembang
library_id	587
collection	Marga Life in South Sumatra in the Past: Puyang Concept Sacrificed and Demythosized
repository_id	17403
city	KOTA PALEMBANG
province	SUMATERA SELATAN
repoId	IOS17403
first_indexed	2022-07-26T01:33:09Z
last_indexed	2022-07-26T01:33:09Z
recordtype	dc
merged_child_boolean	1
_version_	1739401622370385920
score	17.608942

Dataset related to article "Hypofractionated radiation therapy (HFRT) versus conventional fractionated radiation therapy (CRT) for newly diagnosed glioblastoma patients. A propensity score matched analysis"

Lihat Juga