Karakteristik kemoterapi pada keganasan kolorektal di Rumah Sakit Umum Pusat Rujukan Nasional Cipto Mangunkusumo periode Januari 2010 - Agustus 2012 = The characteristic of chemotherapy in colorectal cancer at Cipto Mangunkusumo Hospital January 2010 - August 2012
Main Authors: | Dion Ade Putra, author, Add author: Wifanto Saditya Jeo, supervisor |
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Format: | Bachelors |
Terbitan: |
Fakultas Kedokteran Universitas Indonesia
, 2015
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Subjects: | |
Online Access: |
https://lib.ui.ac.id/detail?id=20417243 |
ctrlnum |
20417243 |
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fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><type>Thesis:Bachelors</type><title>Karakteristik kemoterapi pada keganasan kolorektal di Rumah Sakit Umum Pusat Rujukan Nasional Cipto Mangunkusumo periode Januari 2010 - Agustus 2012 = The characteristic of chemotherapy in colorectal cancer at Cipto Mangunkusumo Hospital January 2010 - August 2012</title><creator>Dion Ade Putra, author</creator><creator>Add author: Wifanto Saditya Jeo, supervisor</creator><publisher>Fakultas Kedokteran Universitas Indonesia</publisher><date>2015</date><subject>Cancer--Chemotherapy</subject><description>[<b>ABSTRAK</b><br> Latar Belakang: Kemoterapi pada kanker kolorektal (KKR) telah mengalami
perkembangan yang amat pesat dalam dua dasawarsa ini. Berikut akan
ditampilkan deskripsi data kemoterapi pada keganasan kolorektal di RSCM
periode Januari 2010-Agustus 2012. Metode: Data didapat dari registrasi rekam
medik Januari 2010-Agustus 2012 secara retrospektif, diolah dengan program
SPSS 11. 5, kemudian dievaluasi. Hasil: Menggambarkan pasien KKR didominasi
jenis kelamin laki-laki 66,7 %. Usia terbanyak pada kategori usia 60-69 tahun.
Ada perbedaan antara kejadian tumor rektum pada pria dan wanita (perbandingan
2:1). Histopatologi terbanyak adalah adenokarsinoma 94,9 %. KKR terletak
paling sering di rektum 48,7 %. Pasien KKR lebih banyak ditemukan pada
stadium III (35,9%), K-Ras terbanyak ditemukan adalah jenis wild-type. Pada 34
kasus (87,2%) KKR dengan nilai CEA di atas normal. Pemberian kemoterapi pada
kanker kolorektal tidak sesuai dengan panduan NCCN 2012 dan Panduan
Nasional Pengelolaan KKR 2004. Efek samping terbanyak adalah vomitus,
anorexia dan dispepsia, sedangkan efek samping lain tersebar merata. Sebanyak
19 pasien (48,7%) tidak menyelesaikan kemoterapi, 11 pasien (28,2%)
menyelesaikan kemoterapi dan 9 orang (23,1%) belum menyelesaikan
kemoterapi. Alasan terbanyak tidak menyelesaikan kemoterapi adalah karena efek
samping. Penggunaan capecitabine seluruhnya mengeluhkan hands and foot
syndrome, sebanyak 7 orang (70%) tingkat 3 dan 3 (30%) orang tingkat 2.
Kesimpulan: Data pasien-pasien KKR di Divisi Bedah Digestif RSCM-FKUI periode Januari 2010-Agustus 2012 menggambarkan bahwa penggunaan regimen kemoterapi belum sepenuhnya mengikuti pedoman kemoterapi pada kanker kolorektal.<b>ABSTRACT</b><b> Background: Chemotherapy in colorectal cancer (CRC) is growing rapidly todays.
We describe the characteristic data about chemotherapy for CRC in Cipto
Mangunkusumo Hospital January 2010-August 2012. Methods: Data was
collected from the medical record center retrospectively from January 2010August
2012, proceesed by SPSS 11. 5 software, then evaluated. Results: Data
described the characteristic of gender is dominated by male (66.7 %) with ratio
2:1 between male and female. Higher incidence is in category 60-69 years old.
The most histological found is adenocarcinoma type (94.9%). The most location
found is in rectum (48.7%). Patient with CRC often found in stadium III (35.9%).
The most K-Ras result found is wild-type. In 34 cases (87.2%) of CRC with
higher CEA values. Data for patients who undergone chemotherapiutic are
inappropriate with standard protocol from NCCN 2012 and Panduan Nasional
Pengelolaan KKR 2004. All patients complained vomitus, anorexia and
dyspepsia, in spite other sides effect are spread evenly. About 19 patients (48.7%)
did not finish chemotherapy, 11 patients (28.2%) finished chemotherapy, and 9
patients (23.1%) are in chemotherapiutic now. Those reasons are patient
waywardness because side effect, medical record error, inappropriate patients
directing for follow up and unavailable regiment. All patients whom use
capecitabine complained hands and foot syndrome with 7 patients (70%) grade 3
and 3 patients (30%) grade 2. Conclusions: From the data we presented, it
describe that data for patients who undergone chemotherapiutic are inappropriate with standard protocol for chemotherapy for CRC., Background: Chemotherapy in colorectal cancer (CRC) is growing rapidly todays.
We describe the characteristic data about chemotherapy for CRC in Cipto
Mangunkusumo Hospital January 2010-August 2012. Methods: Data was
collected from the medical record center retrospectively from January 2010August
2012, proceesed by SPSS 11. 5 software, then evaluated. Results: Data
described the characteristic of gender is dominated by male (66.7 %) with ratio
2:1 between male and female. Higher incidence is in category 60-69 years old.
The most histological found is adenocarcinoma type (94.9%). The most location
found is in rectum (48.7%). Patient with CRC often found in stadium III (35.9%).
The most K-Ras result found is wild-type. In 34 cases (87.2%) of CRC with
higher CEA values. Data for patients who undergone chemotherapiutic are
inappropriate with standard protocol from NCCN 2012 and Panduan Nasional
Pengelolaan KKR 2004. All patients complained vomitus, anorexia and
dyspepsia, in spite other sides effect are spread evenly. About 19 patients (48.7%)
did not finish chemotherapy, 11 patients (28.2%) finished chemotherapy, and 9
patients (23.1%) are in chemotherapiutic now. Those reasons are patient
waywardness because side effect, medical record error, inappropriate patients
directing for follow up and unavailable regiment. All patients whom use
capecitabine complained hands and foot syndrome with 7 patients (70%) grade 3
and 3 patients (30%) grade 2. Conclusions: From the data we presented, it
describe that data for patients who undergone chemotherapiutic are inappropriate with standard protocol for chemotherapy for CRC.]</description><identifier>https://lib.ui.ac.id/detail?id=20417243</identifier><recordID>20417243</recordID></dc>
|
format |
Thesis:Bachelors Thesis |
author |
Dion Ade Putra, author Add author: Wifanto Saditya Jeo, supervisor |
title |
Karakteristik kemoterapi pada keganasan kolorektal di Rumah Sakit Umum Pusat Rujukan Nasional Cipto Mangunkusumo periode Januari 2010 - Agustus 2012 = The characteristic of chemotherapy in colorectal cancer at Cipto Mangunkusumo Hospital January 2010 - August 2012 |
publisher |
Fakultas Kedokteran Universitas Indonesia |
publishDate |
2015 |
topic |
Cancer--Chemotherapy |
url |
https://lib.ui.ac.id/detail?id=20417243 |
contents |
[<b>ABSTRAK</b><br> Latar Belakang: Kemoterapi pada kanker kolorektal (KKR) telah mengalami
perkembangan yang amat pesat dalam dua dasawarsa ini. Berikut akan
ditampilkan deskripsi data kemoterapi pada keganasan kolorektal di RSCM
periode Januari 2010-Agustus 2012. Metode: Data didapat dari registrasi rekam
medik Januari 2010-Agustus 2012 secara retrospektif, diolah dengan program
SPSS 11. 5, kemudian dievaluasi. Hasil: Menggambarkan pasien KKR didominasi
jenis kelamin laki-laki 66,7 %. Usia terbanyak pada kategori usia 60-69 tahun.
Ada perbedaan antara kejadian tumor rektum pada pria dan wanita (perbandingan
2:1). Histopatologi terbanyak adalah adenokarsinoma 94,9 %. KKR terletak
paling sering di rektum 48,7 %. Pasien KKR lebih banyak ditemukan pada
stadium III (35,9%), K-Ras terbanyak ditemukan adalah jenis wild-type. Pada 34
kasus (87,2%) KKR dengan nilai CEA di atas normal. Pemberian kemoterapi pada
kanker kolorektal tidak sesuai dengan panduan NCCN 2012 dan Panduan
Nasional Pengelolaan KKR 2004. Efek samping terbanyak adalah vomitus,
anorexia dan dispepsia, sedangkan efek samping lain tersebar merata. Sebanyak
19 pasien (48,7%) tidak menyelesaikan kemoterapi, 11 pasien (28,2%)
menyelesaikan kemoterapi dan 9 orang (23,1%) belum menyelesaikan
kemoterapi. Alasan terbanyak tidak menyelesaikan kemoterapi adalah karena efek
samping. Penggunaan capecitabine seluruhnya mengeluhkan hands and foot
syndrome, sebanyak 7 orang (70%) tingkat 3 dan 3 (30%) orang tingkat 2.
Kesimpulan: Data pasien-pasien KKR di Divisi Bedah Digestif RSCM-FKUI periode Januari 2010-Agustus 2012 menggambarkan bahwa penggunaan regimen kemoterapi belum sepenuhnya mengikuti pedoman kemoterapi pada kanker kolorektal.<b>ABSTRACT</b><b> Background: Chemotherapy in colorectal cancer (CRC) is growing rapidly todays.
We describe the characteristic data about chemotherapy for CRC in Cipto
Mangunkusumo Hospital January 2010-August 2012. Methods: Data was
collected from the medical record center retrospectively from January 2010August
2012, proceesed by SPSS 11. 5 software, then evaluated. Results: Data
described the characteristic of gender is dominated by male (66.7 %) with ratio
2:1 between male and female. Higher incidence is in category 60-69 years old.
The most histological found is adenocarcinoma type (94.9%). The most location
found is in rectum (48.7%). Patient with CRC often found in stadium III (35.9%).
The most K-Ras result found is wild-type. In 34 cases (87.2%) of CRC with
higher CEA values. Data for patients who undergone chemotherapiutic are
inappropriate with standard protocol from NCCN 2012 and Panduan Nasional
Pengelolaan KKR 2004. All patients complained vomitus, anorexia and
dyspepsia, in spite other sides effect are spread evenly. About 19 patients (48.7%)
did not finish chemotherapy, 11 patients (28.2%) finished chemotherapy, and 9
patients (23.1%) are in chemotherapiutic now. Those reasons are patient
waywardness because side effect, medical record error, inappropriate patients
directing for follow up and unavailable regiment. All patients whom use
capecitabine complained hands and foot syndrome with 7 patients (70%) grade 3
and 3 patients (30%) grade 2. Conclusions: From the data we presented, it
describe that data for patients who undergone chemotherapiutic are inappropriate with standard protocol for chemotherapy for CRC., Background: Chemotherapy in colorectal cancer (CRC) is growing rapidly todays.
We describe the characteristic data about chemotherapy for CRC in Cipto
Mangunkusumo Hospital January 2010-August 2012. Methods: Data was
collected from the medical record center retrospectively from January 2010August
2012, proceesed by SPSS 11. 5 software, then evaluated. Results: Data
described the characteristic of gender is dominated by male (66.7 %) with ratio
2:1 between male and female. Higher incidence is in category 60-69 years old.
The most histological found is adenocarcinoma type (94.9%). The most location
found is in rectum (48.7%). Patient with CRC often found in stadium III (35.9%).
The most K-Ras result found is wild-type. In 34 cases (87.2%) of CRC with
higher CEA values. Data for patients who undergone chemotherapiutic are
inappropriate with standard protocol from NCCN 2012 and Panduan Nasional
Pengelolaan KKR 2004. All patients complained vomitus, anorexia and
dyspepsia, in spite other sides effect are spread evenly. About 19 patients (48.7%)
did not finish chemotherapy, 11 patients (28.2%) finished chemotherapy, and 9
patients (23.1%) are in chemotherapiutic now. Those reasons are patient
waywardness because side effect, medical record error, inappropriate patients
directing for follow up and unavailable regiment. All patients whom use
capecitabine complained hands and foot syndrome with 7 patients (70%) grade 3
and 3 patients (30%) grade 2. Conclusions: From the data we presented, it
describe that data for patients who undergone chemotherapiutic are inappropriate with standard protocol for chemotherapy for CRC.] |
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