Perbedaan ekspresi heparanase pada ameloblastoma tipe campuran, pleksiform, dan folikular Penelitian pada pasien RSCM periode 2009-2014 = Differentiation of heparanase expression inameloblastoma based on histopathological types : Study on ameloblastoma patients in RSCM 2009-2014
| Main Authors: | Rusli, author, Add author: Corputty Johan E.M., supervisor, Add author: Ening Krisnuhoni, supervisor, Add author: Abdul Latief, examiner, Add author: Simanjuntak, Roberto Yance Manahan, examiner |
|---|---|
| Format: | Bachelors |
| Terbitan: |
, 2015
|
| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20424494 |
| ctrlnum |
20424494 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><type>Thesis:Bachelors</type><title>Perbedaan ekspresi heparanase pada ameloblastoma tipe campuran, pleksiform, dan folikular : Penelitian pada pasien RSCM periode 2009-2014 = Differentiation of heparanase expression inameloblastoma based on histopathological types : Study on ameloblastoma patients in RSCM 2009-2014</title><creator>Rusli, author</creator><creator>Add author: Corputty Johan E.M., supervisor</creator><creator>Add author: Ening Krisnuhoni, supervisor</creator><creator>Add author: Abdul Latief, examiner</creator><creator>Add author: Simanjuntak, Roberto Yance Manahan, examiner</creator><publisher/><date>2015</date><subject>Odontogenic tumors</subject><subject>Jaws -- Cysts</subject><description><b>ABSTRAK</b><br>
Latar Belakang: Ameloblastoma merupakan tumor odontogenik yang paling
sering ditemukan pada tulang rahang. Berdasarkan histopatologisnya,
ameloblastoma dapat dikelompokkan menjadi 6 tipe, yaitu tipe folikular,
pleksiformis, akantomatosa, desmoplastik, granular, dan basal. Heparanasepada
ameloblastoma meningkat pada level mRna maupun pada protein, sehingga dapat
menjadi salah satu faktor penting dalam menentukan sifat invasif lokal
ameloblastoma.Hasilpenelitianmenyatakanheparanasememilikiperandalaminvasi
tumor, angiogenesis, danosteoklastogenesis.Tujuan:Untuk
membandingkanekspresiheparanase di
antaraberbagaitipehistopatologiameloblastoma di RSCM.Metode penelitian: 34
blok parafin ameloblastoma didapatkan secara consecutive sampling. Seluruh
sampel dipulas imunohistokimia menggunakan antibodi Heparanase.Hasil:Semua
sampel mempunyai sel-sel yang imunopositif dengan presentase yang beragam,
namun tidak berbeda bermakna secara statistik baik di sitoplasma (p=0,501)
maupun di inti sel (p= 0,247)Kesimpulan: tidak terdapat perbedaan ekspresi heparanase diantara tipe histopatologi ameloblastoma di RSCM.
<hr>
<b>ABSTRACT</b><br>
Background: Ameloblastoma is a common benign odontogenic tumor of the jaw.
Ameloblastoma can be divided into six histopathological types, follicular,
plexiform, acanthomatous, desmoplastic, granular, and basal cell. Heparanasein
ameloblastoma increasing both at mRna and protein level.Recent studies have
found that heparanase is expressed by ameloblastoma and has a role in
ameloblastoma local invasiveness, angiogenesis, andosteoklastogenesis.
Objective: To compare heparananse expression between different
histopathological types of ameloblastoma at RSCM. Material andmethod: 34
paraffin blocks were collected through consecutive sampling and the heparanase
expression were detected using immunohistochemistry. Result: All samples
showed immunopositive cells with vary intensity, however there is no
significantly different of heparanase expression both in sitoplasma (p=0,501) and
nuclear (p= 0,247)Conclusion:There is no different of heparanase expression between histopatological types of ameloblastoma at RSCM.</description><identifier>https://lib.ui.ac.id/detail?id=20424494</identifier><recordID>20424494</recordID></dc>
|
| format |
Thesis:Bachelors Thesis |
| author |
Rusli, author Add author: Corputty Johan E.M., supervisor Add author: Ening Krisnuhoni, supervisor Add author: Abdul Latief, examiner Add author: Simanjuntak, Roberto Yance Manahan, examiner |
| title |
Perbedaan ekspresi heparanase pada ameloblastoma tipe campuran, pleksiform, dan folikular : Penelitian pada pasien RSCM periode 2009-2014 = Differentiation of heparanase expression inameloblastoma based on histopathological types : Study on ameloblastoma patients in RSCM 2009-2014 |
| title_sub |
Penelitian pada pasien RSCM periode 2009-2014 = Differentiation of heparanase expression inameloblastoma based on histopathological types : Study on ameloblastoma patients in RSCM 2009-2014 |
| publishDate |
2015 |
| topic |
Odontogenic tumors Jaws -- Cysts |
| url |
https://lib.ui.ac.id/detail?id=20424494 |
| contents |
<b>ABSTRAK</b><br>
Latar Belakang: Ameloblastoma merupakan tumor odontogenik yang paling
sering ditemukan pada tulang rahang. Berdasarkan histopatologisnya,
ameloblastoma dapat dikelompokkan menjadi 6 tipe, yaitu tipe folikular,
pleksiformis, akantomatosa, desmoplastik, granular, dan basal. Heparanasepada
ameloblastoma meningkat pada level mRna maupun pada protein, sehingga dapat
menjadi salah satu faktor penting dalam menentukan sifat invasif lokal
ameloblastoma.Hasilpenelitianmenyatakanheparanasememilikiperandalaminvasi
tumor, angiogenesis, danosteoklastogenesis.Tujuan:Untuk
membandingkanekspresiheparanase di
antaraberbagaitipehistopatologiameloblastoma di RSCM.Metode penelitian: 34
blok parafin ameloblastoma didapatkan secara consecutive sampling. Seluruh
sampel dipulas imunohistokimia menggunakan antibodi Heparanase.Hasil:Semua
sampel mempunyai sel-sel yang imunopositif dengan presentase yang beragam,
namun tidak berbeda bermakna secara statistik baik di sitoplasma (p=0,501)
maupun di inti sel (p= 0,247)Kesimpulan: tidak terdapat perbedaan ekspresi heparanase diantara tipe histopatologi ameloblastoma di RSCM.
<hr>
<b>ABSTRACT</b><br>
Background: Ameloblastoma is a common benign odontogenic tumor of the jaw.
Ameloblastoma can be divided into six histopathological types, follicular,
plexiform, acanthomatous, desmoplastic, granular, and basal cell. Heparanasein
ameloblastoma increasing both at mRna and protein level.Recent studies have
found that heparanase is expressed by ameloblastoma and has a role in
ameloblastoma local invasiveness, angiogenesis, andosteoklastogenesis.
Objective: To compare heparananse expression between different
histopathological types of ameloblastoma at RSCM. Material andmethod: 34
paraffin blocks were collected through consecutive sampling and the heparanase
expression were detected using immunohistochemistry. Result: All samples
showed immunopositive cells with vary intensity, however there is no
significantly different of heparanase expression both in sitoplasma (p=0,501) and
nuclear (p= 0,247)Conclusion:There is no different of heparanase expression between histopatological types of ameloblastoma at RSCM. |
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Universitas Indonesia |
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JAWA BARAT |
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