Proporsi kepositivan dan genotipe human papillomavirus pada suami pasien kanker serviks serta kesamaan genotipe di antara pasangan di RSUPN Dr. Cipto Mangunkusumo = The positivity proportion and genotype of human papillomavirus in cervical cancer patient's spouse and the genotype concordance between the couples at Dr. Cipto Mangunkusumo Hospital
| Main Authors: | Jonathan Raharjo Subekti, author, Add author: Wresti Indriatmi, supervisor, Add author: Andrijono, supervisor, Add author: Eliza Miranda, supervisor |
|---|---|
| Format: | Bachelors |
| Terbitan: |
Fakultas Kedokteran Universitas Indonesia
, 2016
|
| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20424628 |
| ctrlnum |
20424628 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><type>Thesis:Bachelors</type><title>Proporsi kepositivan dan genotipe human papillomavirus pada suami pasien kanker serviks serta kesamaan genotipe di antara pasangan di RSUPN Dr. Cipto Mangunkusumo = The positivity proportion and genotype of human papillomavirus in cervical cancer patient's spouse and the genotype concordance between the couples at Dr. Cipto Mangunkusumo Hospital</title><creator>Jonathan Raharjo Subekti, author</creator><creator>Add author: Wresti Indriatmi, supervisor</creator><creator>Add author: Andrijono, supervisor</creator><creator>Add author: Eliza Miranda, supervisor</creator><publisher>Fakultas Kedokteran Universitas Indonesia</publisher><date>2016</date><subject>Cervix uteri--Cancer</subject><description><b>ABSTRAK</b><br> Latar belakang. Infeksi human papillomavirus (HPV) pada genital laki-laki selain dapat
menyebabkan kutil kelamin dan kanker penis juga meningkatkan risiko infeksi HPV pada
pasangan. Walaupun saat ini telah terdapat banyak penelitian mengenai peran HPV risiko
tinggi terhadap karsinogenesis serviks dan semakin jelas peran laki-laki sebagai vektor virus
HPV, namun pemeriksaan HPV pada laki-laki belum rutin dilakukan. Penelitian ini bertujuan
mengetahui proporsi kepositivan, variasi genotipe HPV pada suami pasien kanker serviks
serta kesamaan genotipe HPV antara suami pasien kanker serviks yang HPV positif dengan
pasien kanker serviks di RSUPN Dr Cipto Mangunkusumo. Metode. Penelitian potong
lintang. Pemilihan SP dilakukan secara berurutan (consecutive sampling). Sampel diambil
dengan menggunakan kertas amplas dan dacron swab. Pada spesimen dilakukan pemeriksaan
menggunakan HPV express matrix Kalgen®. Hasil. Sebanyak 47 SP dilibatkan dalam
penelitian ini, dengan rerata usia 50,7+10,6 tahun. Dari analisis spesimen diidentifikasi HPV
genital pada 9 (19%) SP, terdiri atas genotipe risiko rendah (3 SP) dan risiko tinggi (6 SP).
Genotipe HPV yang ditemukan adalah 6, 18, 31, 39, 43, 53, dan 56, dengan tipe tersering
adalah 18 dan 43. Tidak didapatkan kesamaan tipe HPV di antara pasangan HPV yang
positif. Kesimpulan. Proporsi kepositivan HPV pada suami pasien kanker serviks sebesar
19% dengan tipe 18 dan 43 paling banyak didapatkan, namun tidak didapatkan kesamaan tipe
HPV antara SP dengan pasien kanker serviks pasangannya.<b>ABSTRACT</b><br> Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.</description><identifier>https://lib.ui.ac.id/detail?id=20424628</identifier><recordID>20424628</recordID></dc>
|
| format |
Thesis:Bachelors Thesis |
| author |
Jonathan Raharjo Subekti, author Add author: Wresti Indriatmi, supervisor Add author: Andrijono, supervisor Add author: Eliza Miranda, supervisor |
| title |
Proporsi kepositivan dan genotipe human papillomavirus pada suami pasien kanker serviks serta kesamaan genotipe di antara pasangan di RSUPN Dr. Cipto Mangunkusumo = The positivity proportion and genotype of human papillomavirus in cervical cancer patient's spouse and the genotype concordance between the couples at Dr. Cipto Mangunkusumo Hospital |
| publisher |
Fakultas Kedokteran Universitas Indonesia |
| publishDate |
2016 |
| topic |
Cervix uteri--Cancer |
| url |
https://lib.ui.ac.id/detail?id=20424628 |
| contents |
<b>ABSTRAK</b><br> Latar belakang. Infeksi human papillomavirus (HPV) pada genital laki-laki selain dapat
menyebabkan kutil kelamin dan kanker penis juga meningkatkan risiko infeksi HPV pada
pasangan. Walaupun saat ini telah terdapat banyak penelitian mengenai peran HPV risiko
tinggi terhadap karsinogenesis serviks dan semakin jelas peran laki-laki sebagai vektor virus
HPV, namun pemeriksaan HPV pada laki-laki belum rutin dilakukan. Penelitian ini bertujuan
mengetahui proporsi kepositivan, variasi genotipe HPV pada suami pasien kanker serviks
serta kesamaan genotipe HPV antara suami pasien kanker serviks yang HPV positif dengan
pasien kanker serviks di RSUPN Dr Cipto Mangunkusumo. Metode. Penelitian potong
lintang. Pemilihan SP dilakukan secara berurutan (consecutive sampling). Sampel diambil
dengan menggunakan kertas amplas dan dacron swab. Pada spesimen dilakukan pemeriksaan
menggunakan HPV express matrix Kalgen®. Hasil. Sebanyak 47 SP dilibatkan dalam
penelitian ini, dengan rerata usia 50,7+10,6 tahun. Dari analisis spesimen diidentifikasi HPV
genital pada 9 (19%) SP, terdiri atas genotipe risiko rendah (3 SP) dan risiko tinggi (6 SP).
Genotipe HPV yang ditemukan adalah 6, 18, 31, 39, 43, 53, dan 56, dengan tipe tersering
adalah 18 dan 43. Tidak didapatkan kesamaan tipe HPV di antara pasangan HPV yang
positif. Kesimpulan. Proporsi kepositivan HPV pada suami pasien kanker serviks sebesar
19% dengan tipe 18 dan 43 paling banyak didapatkan, namun tidak didapatkan kesamaan tipe
HPV antara SP dengan pasien kanker serviks pasangannya.<b>ABSTRACT</b><br> Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genital
warts, penile cancer, but also increase the risk of HPV infection in their spouse. Despite
many current researches on role of high-risk HPV in cervix carcinogenesis and male partner?s
role as HPV vector is well known, HPV examination on male is not yet routinely performed.
The aim of this study is to find the positivity proportion and genotype variant of HPV on
cervical cancer patient?s spouse, and also the genotype concordance between the spouse with
HPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.
Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Sample
was collected with emery paper and dacron swab. The specimen was then analyzed with HPV
express matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age
50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3
subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,
39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance found
between the cervical cancer patient?s spouse with HPV positive and their partners. HPV
genotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.
Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,
with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse. |
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