Perbandingan Keefektifan Adjuvan Inhalasi Lidokain Dengan Spray Lidokain Sebagai Obat Anestetik Lokal Pada Pasien Endoskopi Saluran Cerna Atas = Comparison Between Nebulized Lidocaine And Spray Lidocaine As Local Anesthetic For Adjuvan In Upper Gastrointestinal Endoscopy
| Main Authors: | Tauhid Asri Utomo, author, Add author: Eddy Harijanto, supervisor, Add author: Aldy Heriwardito, supervisor, Add author: Amir Sjarifuddin Madjid, examiner, Add author: Ratna Farida, examiner, Add author: Indro Mulyono, examiner, Add author: Arif Hari Martono Marsaban, examiner, Add author: Rudyanto Sedono, examiner |
|---|---|
| Format: | Bachelors |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20479973 |
| ctrlnum |
20479973 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><type>Thesis:Bachelors</type><title>Perbandingan Keefektifan Adjuvan Inhalasi Lidokain Dengan Spray Lidokain Sebagai Obat Anestetik Lokal Pada Pasien Endoskopi Saluran Cerna Atas = Comparison Between Nebulized Lidocaine And Spray Lidocaine As Local Anesthetic For Adjuvan In Upper Gastrointestinal Endoscopy</title><creator>Tauhid Asri Utomo, author</creator><creator>Add author: Eddy Harijanto, supervisor</creator><creator>Add author: Aldy Heriwardito, supervisor</creator><creator>Add author: Amir Sjarifuddin Madjid, examiner</creator><creator>Add author: Ratna Farida, examiner</creator><creator>Add author: Indro Mulyono, examiner</creator><creator>Add author: Arif Hari Martono Marsaban, examiner</creator><creator>Add author: Rudyanto Sedono, examiner</creator><publisher/><date>2018</date><subject>Nebulizers and Vaporizers</subject><subject>Anesthetics -- pharmacology</subject><description><b>ABSTRAK</b><br>
Latar Belakang </strong>: Penggunaan <em>spray</em> lidokain dengan obat anestetik intravena merupakan pilihan untuk sedasi pada endoskopi saluran cerna atas. Tetapi terdapat ketidaknyamanan dari pasien mengenai penggunaan <em>spray </em>lidokain. Inhalasi lidokain merupakan pilihan alternatif anestetik lokal. Penelitian ini bertujuan untuk membandingkan keefektifan dari <em>spray</em> lidokain dan inhalasi lidokain pada endoskopi saluran cerna atas.</p><p><strong>Metoda : </strong>150 pasien yang menjalani endoskopi saluran cera atas dengan sedasi di RSUPN Cipto Mangunkusumo sejak November 2017 hingga April 2018, dengan kesan ASA I-II, BMI 18,5-29,9, dan setuju untuk mengikuti penelitian, dilakukan randomisasi dan dibagi menjadi 2 grup yang akan mendapatkan 1,5 mg/kgbb <em>spray </em>lidokain atau 1,5 mg.kgbb inhalasi lidokain. Untuk sedasi akan diberikan fentanyl 1 mcg.kgbb dan propofol 1,5 mg/kgbb bolus pada kedua grup . Tiap kejadian <em>gag reflex </em>dan penambahan dosis propofol akan dicatat.</p><p><strong>Hasil </strong>: <em>Gag reflex </em>terjadi sebanyak 1,3 % total pasien di grup inhalasi lidokain dan 30,7% pada grup <em>spray </em>lidokain (P<0,001). Rerata <em>rescue dose </em>propofol yang didapatkan pada grup inhalasi lidokain (0,67 ± 5,77 mg/kg) dan (11 ± 17,9 mg/kg) pada grup <em>spray </em>lidokain. Parameter lain seperti usia, jenis kelamin, kategori ASA, BMI didapatkan tidak signifikan.</p><p><strong>Simpulan </strong>: Inhalasi lidokain lebih efektif sebagai anestetik lokal dibandingkan <em>spray </em>lidokain sebagai adjuvan pada endoskopi saluran cerna atas.
<hr>
<b>ABSTRACT</b><br>
Background </strong>: Combination of spray lidocaine and intravenous anesthetic was the choice for upper gastrointestinal endoscopy (UGE). However, spraying lidocaine was found uncomfortable to the patient. Nebulized lidocaine was the alternative for local anesthetic. This study aimed to compare the effectiveness of spraying and nebulized lidocaine for patients undergoing UGE.</p><p><strong>Methods</strong> : 150 patients undergoing UGE under sedation at Cipto Mangunkusumo National Hospital from November 2017 until April 2018, with physical status ASA I-II, BMI 18,5-29,9, and agree to join the experiment, were randomized to receive either 1,5 mg/kg of spray lidocaine or 1,5 mg/kg of nebulized lidocaine. Combined sedation was achieved using fentanyl 1 mcg/kg and Propofol 1,5 mg/kg IV boluses. Every gag reflex occurred and rescue dose of propofol administered were recorded.</p><p><strong>Result</strong> : Gag reflex occurred 1,3% in nebulized lidocaine group and 30,7% occurred in spray lidocaine (P < 0,001). Mean rescue dose of propofol in nebulized lidocaine group (0,67 ± 5,77 mg/kg) and (11 ± 17,9 mg/kg) in spray group. Outcomes parameters including sex, age, ASA category, BMI were statistically unsignificant..</p><p><strong>Discussion</strong> : We think inability of spray lidocaine to resist gag reflex is because the process of spraying should be equal from each side of vocal cord, pharynx and larynx. Nebulization could split the lidocaine into small particle, so the spread of the lidocaine will be spread evenly.</p><p><strong>Conclusion</strong> : Nebulized lidocaine is more effective as local anesthetic than spray lidocaine for adjuvant in UGE.</p></description><identifier>https://lib.ui.ac.id/detail?id=20479973</identifier><recordID>20479973</recordID></dc>
|
| format |
Thesis:Bachelors Thesis |
| author |
Tauhid Asri Utomo, author Add author: Eddy Harijanto, supervisor Add author: Aldy Heriwardito, supervisor Add author: Amir Sjarifuddin Madjid, examiner Add author: Ratna Farida, examiner Add author: Indro Mulyono, examiner Add author: Arif Hari Martono Marsaban, examiner Add author: Rudyanto Sedono, examiner |
| title |
Perbandingan Keefektifan Adjuvan Inhalasi Lidokain Dengan Spray Lidokain Sebagai Obat Anestetik Lokal Pada Pasien Endoskopi Saluran Cerna Atas = Comparison Between Nebulized Lidocaine And Spray Lidocaine As Local Anesthetic For Adjuvan In Upper Gastrointestinal Endoscopy |
| publishDate |
2018 |
| topic |
Nebulizers and Vaporizers Anesthetics -- pharmacology |
| url |
https://lib.ui.ac.id/detail?id=20479973 |
| contents |
<b>ABSTRAK</b><br>
Latar Belakang </strong>: Penggunaan <em>spray</em> lidokain dengan obat anestetik intravena merupakan pilihan untuk sedasi pada endoskopi saluran cerna atas. Tetapi terdapat ketidaknyamanan dari pasien mengenai penggunaan <em>spray </em>lidokain. Inhalasi lidokain merupakan pilihan alternatif anestetik lokal. Penelitian ini bertujuan untuk membandingkan keefektifan dari <em>spray</em> lidokain dan inhalasi lidokain pada endoskopi saluran cerna atas.</p><p><strong>Metoda : </strong>150 pasien yang menjalani endoskopi saluran cera atas dengan sedasi di RSUPN Cipto Mangunkusumo sejak November 2017 hingga April 2018, dengan kesan ASA I-II, BMI 18,5-29,9, dan setuju untuk mengikuti penelitian, dilakukan randomisasi dan dibagi menjadi 2 grup yang akan mendapatkan 1,5 mg/kgbb <em>spray </em>lidokain atau 1,5 mg.kgbb inhalasi lidokain. Untuk sedasi akan diberikan fentanyl 1 mcg.kgbb dan propofol 1,5 mg/kgbb bolus pada kedua grup . Tiap kejadian <em>gag reflex </em>dan penambahan dosis propofol akan dicatat.</p><p><strong>Hasil </strong>: <em>Gag reflex </em>terjadi sebanyak 1,3 % total pasien di grup inhalasi lidokain dan 30,7% pada grup <em>spray </em>lidokain (P<0,001). Rerata <em>rescue dose </em>propofol yang didapatkan pada grup inhalasi lidokain (0,67 ± 5,77 mg/kg) dan (11 ± 17,9 mg/kg) pada grup <em>spray </em>lidokain. Parameter lain seperti usia, jenis kelamin, kategori ASA, BMI didapatkan tidak signifikan.</p><p><strong>Simpulan </strong>: Inhalasi lidokain lebih efektif sebagai anestetik lokal dibandingkan <em>spray </em>lidokain sebagai adjuvan pada endoskopi saluran cerna atas.
<hr>
<b>ABSTRACT</b><br>
Background </strong>: Combination of spray lidocaine and intravenous anesthetic was the choice for upper gastrointestinal endoscopy (UGE). However, spraying lidocaine was found uncomfortable to the patient. Nebulized lidocaine was the alternative for local anesthetic. This study aimed to compare the effectiveness of spraying and nebulized lidocaine for patients undergoing UGE.</p><p><strong>Methods</strong> : 150 patients undergoing UGE under sedation at Cipto Mangunkusumo National Hospital from November 2017 until April 2018, with physical status ASA I-II, BMI 18,5-29,9, and agree to join the experiment, were randomized to receive either 1,5 mg/kg of spray lidocaine or 1,5 mg/kg of nebulized lidocaine. Combined sedation was achieved using fentanyl 1 mcg/kg and Propofol 1,5 mg/kg IV boluses. Every gag reflex occurred and rescue dose of propofol administered were recorded.</p><p><strong>Result</strong> : Gag reflex occurred 1,3% in nebulized lidocaine group and 30,7% occurred in spray lidocaine (P < 0,001). Mean rescue dose of propofol in nebulized lidocaine group (0,67 ± 5,77 mg/kg) and (11 ± 17,9 mg/kg) in spray group. Outcomes parameters including sex, age, ASA category, BMI were statistically unsignificant..</p><p><strong>Discussion</strong> : We think inability of spray lidocaine to resist gag reflex is because the process of spraying should be equal from each side of vocal cord, pharynx and larynx. Nebulization could split the lidocaine into small particle, so the spread of the lidocaine will be spread evenly.</p><p><strong>Conclusion</strong> : Nebulized lidocaine is more effective as local anesthetic than spray lidocaine for adjuvant in UGE.</p> |
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JAWA BARAT |
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