Mcngcrahui peran terapi gizi adekuat pascabedah pada kadar glukosa sewaktu dan malondialdehyde plasma pasien bedah digestif = Efect of postoperative adequate nutrition therapy on plasma glucose and malondialdehyde levels in digestive surgery patients
| Main Authors: | Monique Carolina Widjaja, author, Add author: Sri Sukmaniah, supervisor, Add author: Aryono D. Pusponegoro, supervisor, Add author: Ninik Mudjihartini, examiner, Add author: Retno Asti Werdhani, examiner, Add author: Johana Titus, examiner, Add author: Lalisang, Toar J.M., examiner |
|---|---|
| Format: | Masters Thesis |
| Terbitan: |
Universitas Indonesia
, 2009
|
| Online Access: |
https://lib.ui.ac.id/detail?id=20340208 |
Daftar Isi:
- Mcngetahui peran terapi gizi adkuat pascabedah sclama enam hari bcrturut-turut pada kadar glukosa darah sewalctu dan malondialdehyde plasma pada pasien bedah digestii Penclitian ini merupakan uji klinis paralcl. mcmbandingkan kelompok yang mendapat terapi gizi adelcuat pascabedah (P) dcngan kelompok yang mcndapatkan diet standar RSUPNCM (K). Scbanyak 17 pasien pascabedah digcstif yang dirawat di ruang perawatan bcdah kelas III RSUPNCM yang memenuhi kriteria dibagi dalam dua kclompok secara randomisasi blok. Data yang cliambil dari catatan medik pada awal perlalruan meliputi usia, jcnis kclamin, lama operasi, jenis opcrasi, skor ASA, dan jumlah pcrdarahan. Data asupan cnergi dan protein dengan food record, pemcfiksaan antropomctri (BB, PB dan IMT), dan laboratorium (kadar GDS dan MDA plasma) dilakukan pada awal dan akhir perlakuan. Analisis data menggunakan uji t tidak berpasangan dan uji Mann Whitney dengan batas kemaknaan 5%. Sebanyak 9 orang kelompok P dan 8 orang kelompok K dengan rcrata usia 38,821-10,89 tahun mengikuti penelitian sccara lengkap. .lenis opemsi tcrbanyak yang dijalani subyek adalah reseksi-anastomosis. Lama opcrasi subyek pcrlakuan lergolong lama dan subyek kontrol tcrgolong singkat, Jumlah pcrdarahan tergolong sedikit. Data awal tidal-c mcnunjukkan pcrbedaan bcrmakna (p> 0,05). Setelah enam hari perlakuan, diclapatkan persentasc asupan cncrgi dan protein dibandingkan kcbutuhan total tcrmasuk kategori adekuat pada kelompok perlakuan dan tidal: adckuat pada kelompok konlrol, dan pcrbcdaan ini bermakna (p<0,05). Pada kedua kelompok didapatkan peningkatan kadar GDS plasma yang lebih tinggi pada kelompok kontrol, namun secara statistik tidak bermakna (p> 0,05). Pada kclompok perlakuan tcrdapat pcnurunan kadar MDA plasma sedangkan pada kclompok kontrol terdapat peningkatan MDA plasma, mcskipun sccara statistik tidak bermakna (p>0,05). Pada kedua kelompok didapatkan pcningkatan kadar GDS plasma yang lebih tinggi pada kclompok kontrol, namun secara statistik tidalc bermakna serta didapatkan penurunan MDA plasma pada lcelompok pcrlakuan. Penelitian ini memperlihatkan tcrapi gizi dapat memperbaiki strcs mctabolik dan oksidatif lebih balk dibanclingkan tanpa terapi gizi. bcdah digestif, rerapi gizi adekual, glukosa darah sewaktu. malondialdehyde <hr> To investigate the effect of postoperative adequate nutrition therapy duriig six days on plasma glucose and inalondialdehyde leves in digestive surgery patients. The study was a parallel randomized clinical trial which compared the treatment group received postoperative adequate nutrition therapy (P) and the control group received hospital standard diet (K). Seventeen subjects postoperative digestive surgery admitted to Surgery Ward of Dr. Cipto Mangunkusumo Hospital whofultilled the study criteria, were divided into two groups using block rzuidomization. Data collection taken from medical record at the begimiing of intervention were age, gender, duration of surgery, type of surgery, ASA score, and the amount of blood loss during surgery. Data of energy, and protein intake using food record, anthropometry (body weight, body length, and body mass index), and laboratory findings (plasma glucose and nialondialdehyde levels) were done before and after intervention. For statistical analysis, uupaired t-test and Mann Whitney were used. The level of significance was 5%. Nine subjects in the treatment group and eight subjects inthe control group whose mean of age is 3882310.89 years old completed the study. The most type of surgery was resection-anastomosis. The duration of surgery was catagorized as longtime in P and shortime in K groups. The amount of blood loss during surgery was little for both groups. The characteristic of the two groups were closely mathced at base line (p> 0.05). After six days intervention. the percentage of energy and protein intake in treatment group were adequate in appropriate to the requirement, and these were statistically significant compared to control group (p<0.05). There were increase of plasma glucose levels in both groups which was higher in control group, however the increase was not statistically significant (p>0.05). Plasma levels of MDA were decrease in treatment group while in control group were increase eventhough the changes between the two groups were not statistically significant (p>0.05). There were increase of plasma glucose level which was higher in the control group, although has not statistically significant and there were decrease of plasma MDA levels in treatment group. This study revealed that nutrition therapy can improve metabolic and oxidative stress better than those without nutrition therapy. digestive surgery, adequate nutrition therapy, plasma glucose, malondialdehyde.