Sintesis Kuersetin Terklorinasi Terklorinasi dan Aktivitas Perlindung terhadap Tukak Lambung (Synthesis and Gastric Ulcer Protective Activity of Chlorinated Quercetin)
| Main Authors: | Rina Herowati, Tutus Gusdinar, R.E. Kartasasmita, I Ketut Adniana |
|---|---|
| Format: | Book |
| Terbitan: |
Fakultas Farmasi UGM
, 2009
|
| Subjects: | |
| Online Access: |
https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=29963 |
| ctrlnum |
slims-29963 |
|---|---|
| fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>Sintesis Kuersetin Terklorinasi Terklorinasi dan Aktivitas Perlindung terhadap Tukak Lambung (Synthesis and Gastric Ulcer Protective Activity of Chlorinated Quercetin)</title><creator>Rina Herowati</creator><creator>Tutus Gusdinar</creator><creator>R.E. Kartasasmita</creator><creator>I Ketut Adniana</creator><subject>STOMACH ULCER</subject><subject>QUERCETIN</subject><publisher>Fakultas Farmasi UGM</publisher><date>2009</date><language/><type>Book:Book</type><identifier>https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=29963</identifier><identifier>0126-1037</identifier><identifier>Majalah Farmasi Indonesia:20(4):163-169</identifier><description>Gastrointestinal toxicity due to non-steroid anti-inflamatory drugs can be inhibited by the compounds that have antioxidant activity. Quercetin is a flavonoid that has antioxidant activity and protection effect against ulcer. Chlorination of quercetin anhanced the antioxidant. This study aims to obatin the chlorinated derivative of quercetin and examine the protection effect against acetosal-induced gestric ulcer. Chlorination was done by the addition of chlorine at room temperature. Ulcer induction was carried out on rats by oral administration of acetosal. Incidence of gastric ulcer were determined by macroscopic and microscopic observation. Chlorination of quercetin with chlroine gas produced 6-chloroqueretin as major product. The protection effect against acetosal-induced gastric ulcer of this compound was higher than quercatin.</description><coverage>Yogyakarta</coverage><image>https://perpustakaan.badankebijakan.kemkes.go.id//images/default/image.png</image><recordID>slims-29963</recordID></dc>
|
| format |
Book:Book Book |
| author |
Rina Herowati Tutus Gusdinar R.E. Kartasasmita I Ketut Adniana |
| title |
Sintesis Kuersetin Terklorinasi Terklorinasi dan Aktivitas Perlindung terhadap Tukak Lambung (Synthesis and Gastric Ulcer Protective Activity of Chlorinated Quercetin) |
| publisher |
Fakultas Farmasi UGM |
| publishDate |
2009 |
| topic |
STOMACH ULCER QUERCETIN |
| url |
https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=29963 |
| contents |
Gastrointestinal toxicity due to non-steroid anti-inflamatory drugs can be inhibited by the compounds that have antioxidant activity. Quercetin is a flavonoid that has antioxidant activity and protection effect against ulcer. Chlorination of quercetin anhanced the antioxidant. This study aims to obatin the chlorinated derivative of quercetin and examine the protection effect against acetosal-induced gestric ulcer. Chlorination was done by the addition of chlorine at room temperature. Ulcer induction was carried out on rats by oral administration of acetosal. Incidence of gastric ulcer were determined by macroscopic and microscopic observation. Chlorination of quercetin with chlroine gas produced 6-chloroqueretin as major product. The protection effect against acetosal-induced gastric ulcer of this compound was higher than quercatin. |
| id |
IOS19738.slims-29963 |
| institution |
Badan Kebijakan Pembangunan Kesehatan |
| institution_id |
12 |
| institution_type |
library:special library |
| library |
Perpustakaan Badan Penelitian dan Pengembangan Kesehatan |
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16 |
| collection |
Katalog Perpustakaan Badan Kebijakan Pembangunan Kesehatan |
| repository_id |
19738 |
| subject_area |
Kesehatan Kesehatan Masyarakat Kebijakan Kesehatan |
| city |
JAKARTA PUSAT |
| province |
DKI JAKARTA |
| repoId |
IOS19738 |
| first_indexed |
2023-12-11T10:32:44Z |
| last_indexed |
2023-12-11T10:32:44Z |
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dc |
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1785082815262490624 |
| score |
17.610285 |