The effect of prednisone on sertoli cell of contralateral testicular torsion
Main Authors: | Suwandi Sugandi, Aaron Tigor Sihombing, Anglita Yantisetiasti, Dandy Tanuwidjaja, Betthy S. Hernowo |
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Format: | Book 4p |
Terbitan: |
The Indonesian Urological Association
, 2012
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Subjects: | |
Online Access: |
https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=35242 |
ctrlnum |
slims-35242 |
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fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>The effect of prednisone on sertoli cell of contralateral testicular torsion</title><creator>Suwandi Sugandi</creator><creator>Aaron Tigor Sihombing</creator><creator>Anglita Yantisetiasti</creator><creator>Dandy Tanuwidjaja</creator><creator>Betthy S. Hernowo</creator><subject>TORSION</subject><subject>SPERMATIC CORD</subject><subject>SERTOLI CELLS</subject><subject>PREDNISONE</subject><publisher>The Indonesian Urological Association</publisher><date>2012</date><language/><type>Book:Book</type><identifier>https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=35242</identifier><identifier>0853-442x</identifier><identifier>Indonesian Journal of Urology : 19 (2) 2012, 64-67</identifier><description>Objective: To evaluate the effect of prednisone in unilateral testicular torsion on Sertoli cell quality of contralateral testis. Material & Method: Thirty Wistar rats were divided into three groups i.e. group A (sham procedure), group B (unilateral torsion + orchiectomy after 6 hours), and group C (unilateral torsion + orchiectomy after 24 hours). Group B and C were further divided into subgroup with and without Prednisone administration. Prednisone was given orally once a day an hour after torsion, continued till one month later Orchiectomy of contralateral testis was performed one month later Those testes were examined by a pathologist. Results: In group A, no abnormality on Sertoli cell quality was found. There is significant difference among groups in Sertoli cell quality (p = 0,01). Ischemic time is associated with Sertoli cell quality (2 rats with severe damage in group C and none in group B). In group B and C, prednisone administration inhibited Sertoli cell damage. Prednisone administration in 6 hours group gave better results than 24 hours group (3 rats vs I rat with good Sertoli cell quality). Conclusion: Sertoli cell in contralateral testis is significantly affected by unilateral testicular torsion. Prednisone inhibit Sertoli cells damage. Ischemic time affected Sertoli cell quality of contralateral testis and respond to prednisone.Keywords: Prednisone, unilateral testicular torsion, sertoli cell.</description><coverage>Surabaya</coverage><type>Other:4p</type><image>https://perpustakaan.badankebijakan.kemkes.go.id//images/default/image.png</image><recordID>slims-35242</recordID></dc>
|
format |
Book:Book Book Other:4p Other |
author |
Suwandi Sugandi Aaron Tigor Sihombing Anglita Yantisetiasti Dandy Tanuwidjaja Betthy S. Hernowo |
title |
The effect of prednisone on sertoli cell of contralateral testicular torsion |
publisher |
The Indonesian Urological Association |
publishDate |
2012 |
topic |
TORSION SPERMATIC CORD SERTOLI CELLS PREDNISONE |
url |
https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=35242 |
contents |
Objective: To evaluate the effect of prednisone in unilateral testicular torsion on Sertoli cell quality of contralateral testis. Material & Method: Thirty Wistar rats were divided into three groups i.e. group A (sham procedure), group B (unilateral torsion + orchiectomy after 6 hours), and group C (unilateral torsion + orchiectomy after 24 hours). Group B and C were further divided into subgroup with and without Prednisone administration. Prednisone was given orally once a day an hour after torsion, continued till one month later Orchiectomy of contralateral testis was performed one month later Those testes were examined by a pathologist. Results: In group A, no abnormality on Sertoli cell quality was found. There is significant difference among groups in Sertoli cell quality (p = 0,01). Ischemic time is associated with Sertoli cell quality (2 rats with severe damage in group C and none in group B). In group B and C, prednisone administration inhibited Sertoli cell damage. Prednisone administration in 6 hours group gave better results than 24 hours group (3 rats vs I rat with good Sertoli cell quality). Conclusion: Sertoli cell in contralateral testis is significantly affected by unilateral testicular torsion. Prednisone inhibit Sertoli cells damage. Ischemic time affected Sertoli cell quality of contralateral testis and respond to prednisone.Keywords: Prednisone, unilateral testicular torsion, sertoli cell. |
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Badan Kebijakan Pembangunan Kesehatan |
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JAKARTA PUSAT |
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DKI JAKARTA |
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2023-12-11T10:33:39Z |
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