The effect of prednisone on sertoli cell of contralateral testicular torsion

Main Authors: Suwandi Sugandi, Aaron Tigor Sihombing, Anglita Yantisetiasti, Dandy Tanuwidjaja, Betthy S. Hernowo
Format: Book 4p
Terbitan: The Indonesian Urological Association , 2012
Subjects:
Online Access: https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=35242
ctrlnum slims-35242
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>The effect of prednisone on sertoli cell of contralateral testicular torsion</title><creator>Suwandi Sugandi</creator><creator>Aaron Tigor Sihombing</creator><creator>Anglita Yantisetiasti</creator><creator>Dandy Tanuwidjaja</creator><creator>Betthy S. Hernowo</creator><subject>TORSION</subject><subject>SPERMATIC CORD</subject><subject>SERTOLI CELLS</subject><subject>PREDNISONE</subject><publisher>The Indonesian Urological Association</publisher><date>2012</date><language/><type>Book:Book</type><identifier>https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&amp;id=35242</identifier><identifier>0853-442x</identifier><identifier>Indonesian Journal of Urology : 19 (2) 2012, 64-67</identifier><description>Objective: To evaluate the effect of prednisone in unilateral testicular torsion on Sertoli cell quality of contralateral testis. Material &amp; Method: Thirty Wistar rats were divided into three groups i.e. group A (sham procedure), group B (unilateral torsion + orchiectomy after 6 hours), and group C (unilateral torsion + orchiectomy after 24 hours). Group B and C were further divided into subgroup with and without Prednisone administration. Prednisone was given orally once a day an hour after torsion, continued till one month later Orchiectomy of contralateral testis was performed one month later Those testes were examined by a pathologist. Results: In group A, no abnormality on Sertoli cell quality was found. There is significant difference among groups in Sertoli cell quality (p = 0,01). Ischemic time is associated with Sertoli cell quality (2 rats with severe damage in group C and none in group B). In group B and C, prednisone administration inhibited Sertoli cell damage. Prednisone administration in 6 hours group gave better results than 24 hours group (3 rats vs I rat with good Sertoli cell quality). Conclusion: Sertoli cell in contralateral testis is significantly affected by unilateral testicular torsion. Prednisone inhibit Sertoli cells damage. Ischemic time affected Sertoli cell quality of contralateral testis and respond to prednisone.Keywords: Prednisone, unilateral testicular torsion, sertoli cell.</description><coverage>Surabaya</coverage><type>Other:4p</type><image>https://perpustakaan.badankebijakan.kemkes.go.id//images/default/image.png</image><recordID>slims-35242</recordID></dc>
format Book:Book
Book
Other:4p
Other
author Suwandi Sugandi
Aaron Tigor Sihombing
Anglita Yantisetiasti
Dandy Tanuwidjaja
Betthy S. Hernowo
title The effect of prednisone on sertoli cell of contralateral testicular torsion
publisher The Indonesian Urological Association
publishDate 2012
topic TORSION
SPERMATIC CORD
SERTOLI CELLS
PREDNISONE
url https://perpustakaan.badankebijakan.kemkes.go.id//index.php?p=show_detail&id=35242
contents Objective: To evaluate the effect of prednisone in unilateral testicular torsion on Sertoli cell quality of contralateral testis. Material & Method: Thirty Wistar rats were divided into three groups i.e. group A (sham procedure), group B (unilateral torsion + orchiectomy after 6 hours), and group C (unilateral torsion + orchiectomy after 24 hours). Group B and C were further divided into subgroup with and without Prednisone administration. Prednisone was given orally once a day an hour after torsion, continued till one month later Orchiectomy of contralateral testis was performed one month later Those testes were examined by a pathologist. Results: In group A, no abnormality on Sertoli cell quality was found. There is significant difference among groups in Sertoli cell quality (p = 0,01). Ischemic time is associated with Sertoli cell quality (2 rats with severe damage in group C and none in group B). In group B and C, prednisone administration inhibited Sertoli cell damage. Prednisone administration in 6 hours group gave better results than 24 hours group (3 rats vs I rat with good Sertoli cell quality). Conclusion: Sertoli cell in contralateral testis is significantly affected by unilateral testicular torsion. Prednisone inhibit Sertoli cells damage. Ischemic time affected Sertoli cell quality of contralateral testis and respond to prednisone.Keywords: Prednisone, unilateral testicular torsion, sertoli cell.
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first_indexed 2023-12-11T10:33:39Z
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