Secondary Metabolite of Aspergillus fumigatus, Endophytic Fungi of the Medicinal Plant Garcinia griffithii

Main Authors: Elfita Elfita; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Indralaya, Palembang 30662, Indonesia, Tri Indah; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Indralaya, Palembang 30662, Indonesia
Format: Article application/pdf eJournal
Bahasa: eng
Terbitan: Directorate of Research and Community Engagement, Universitas Indonesia , 2012
Subjects:
Online Access: http://journal.ui.ac.id/index.php/science/article/view/1061
Daftar Isi:
  • The endophytic fungi Aspergillus fumigatus was isolated from the tissues of the fruits of Garcinia griffithii. The fungal strain was identified from the colony, and it was characteristic of cell morphology. The ethyl acetate extracts derived from fungus cultures showed major spots on TLC under UV light, which was continued to the isolation of the secondary metabolites. The structure of the isolated compound was elucidated on the basis of NMR analyses (1H-NMR, 13C-NMR, HMQC, HMBC and H-H COSY). The compounds were identified as: 4,6-dihydroxy, 3,8a-dimethyl-1-oxo- 5-(3’-oxobutan-2’-yl)-1,4,4a,5,6,8a-hexahydronaphthalen-2-yl-1”,2”-dimethyl-5”-(2”’-methylprop 1”’-enyl)cyclopentanecarboxylate.