UJI AKTIVITAS ANTIJAMUR MINYAK ATSIRI BAWANG BOMBAY (ALLIUM CEPA L. VAR. CEPA)TERHADAP ISOLAT KLINIS CANDIDA ALBICANS
| Main Author: | Rahmad Winandar |
|---|---|
| Format: | Bachelors |
| Bahasa: | ind |
| Terbitan: |
Fakultas Kedokteran
, 2015
|
| Subjects: | |
| Online Access: |
http://etd.unsyiah.ac.id//index.php?p=show_detail&id=13927 |
| ctrlnum |
slims-13927 |
|---|---|
| fullrecord |
<?xml version="1.0"?>
<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title>UJI AKTIVITAS ANTIJAMUR MINYAK ATSIRI BAWANG BOMBAY (ALLIUM CEPA L. VAR. CEPA)TERHADAP ISOLAT KLINIS CANDIDA ALBICANS</title><creator>Rahmad Winandar</creator><subject>ONION</subject><subject>MEDICINAL PLANTS</subject><subject>ESSENTIAL OIL</subject><publisher>Fakultas Kedokteran</publisher><date>2015</date><language>ind</language><type>Thesis:Bachelors</type><identifier>http://etd.unsyiah.ac.id//index.php?p=show_detail&id=13927</identifier><description>ABSTRAKCandida albicans merupakan salah satu jamur penyebab infeksi oportunistik pada manusiadan telahdilaporkan resisten terhadap beberapa golongan obat antijamur. Penggunaan bahan baku tumbuhan sebagai agen antimikroba dapat mencegah resistensi antimikroba. Bawang Bombay (Allium cepa L.Var. Cepa) merupakan salah satu tumbuhan yang mengandung komponen senyawa sulfur yang disebut thiosulfinate atau isothiocyanates. Senyawa tersebut diketahui memiliki efek antibakteri maupun antijamur. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur minyak atsiri bawang Bombay terhadap isolat klinis C. albicans. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 5 kelompok perlakuan (konsentrasi 1%, 5%, 10%, 15% dan 20%) dan 1 kelompok kontrol negatif (akuades dan Tween 80) dengan 4 kali pengulangan. Uji aktivitas antijamur dilakukan dengan metode difusi cakram Kirby-Bauer. Hasil penelitian menunjukkan minyak atsiri bawang Bombay tidak memiliki daya hambat terhadap isolat klinis C. albicans.Kata Kunci : Candida albicans, Allium cepa L. Var. Cepa, difusi cakram.ABSTRACTCandida albicans is one of the fungi that cause opportunistic infections in humans and reported resistant to several classes of antifungal drugs. The use of natural products as an antimicrobial agent can prevent antimicrobial resistance. Onion (Allium cepa L. Var. Cepa) is one of the plants that contain sulfur compounds component called thiosulfinate or isothiocyanates. These compounds are known to have antibacterial and antifungal effects. The aims of this study was to determine the antifungal activity of the essential oil of onion against clinical isolates of C. albicans. This study used a completely randomized design (CRD), which consists of five treatment groups (concentration of 1%, 5%, 10%, 15% and 20%) and one negative control group (distilled water and Tween 80) with 4 repetitions. Antifungal activity test was conducted by using Kirby-Bauer disc diffusion method. The results showed that onion essential oil has no inhibitory effect on clinical isolates of C. albicans.Keyword : Candida albicans, Allium cepa L. Var. Cepa, disc diffusion.</description><description>Banda Aceh</description><recordID>slims-13927</recordID></dc>
|
| language |
ind |
| format |
Thesis:Bachelors Thesis |
| author |
Rahmad Winandar |
| title |
UJI AKTIVITAS ANTIJAMUR MINYAK ATSIRI BAWANG BOMBAY (ALLIUM CEPA L. VAR. CEPA)TERHADAP ISOLAT KLINIS CANDIDA ALBICANS |
| publisher |
Fakultas Kedokteran |
| publishDate |
2015 |
| topic |
ONION MEDICINAL PLANTS ESSENTIAL OIL |
| url |
http://etd.unsyiah.ac.id//index.php?p=show_detail&id=13927 |
| contents |
ABSTRAKCandida albicans merupakan salah satu jamur penyebab infeksi oportunistik pada manusiadan telahdilaporkan resisten terhadap beberapa golongan obat antijamur. Penggunaan bahan baku tumbuhan sebagai agen antimikroba dapat mencegah resistensi antimikroba. Bawang Bombay (Allium cepa L.Var. Cepa) merupakan salah satu tumbuhan yang mengandung komponen senyawa sulfur yang disebut thiosulfinate atau isothiocyanates. Senyawa tersebut diketahui memiliki efek antibakteri maupun antijamur. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur minyak atsiri bawang Bombay terhadap isolat klinis C. albicans. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 5 kelompok perlakuan (konsentrasi 1%, 5%, 10%, 15% dan 20%) dan 1 kelompok kontrol negatif (akuades dan Tween 80) dengan 4 kali pengulangan. Uji aktivitas antijamur dilakukan dengan metode difusi cakram Kirby-Bauer. Hasil penelitian menunjukkan minyak atsiri bawang Bombay tidak memiliki daya hambat terhadap isolat klinis C. albicans.Kata Kunci : Candida albicans, Allium cepa L. Var. Cepa, difusi cakram.ABSTRACTCandida albicans is one of the fungi that cause opportunistic infections in humans and reported resistant to several classes of antifungal drugs. The use of natural products as an antimicrobial agent can prevent antimicrobial resistance. Onion (Allium cepa L. Var. Cepa) is one of the plants that contain sulfur compounds component called thiosulfinate or isothiocyanates. These compounds are known to have antibacterial and antifungal effects. The aims of this study was to determine the antifungal activity of the essential oil of onion against clinical isolates of C. albicans. This study used a completely randomized design (CRD), which consists of five treatment groups (concentration of 1%, 5%, 10%, 15% and 20%) and one negative control group (distilled water and Tween 80) with 4 repetitions. Antifungal activity test was conducted by using Kirby-Bauer disc diffusion method. The results showed that onion essential oil has no inhibitory effect on clinical isolates of C. albicans.Keyword : Candida albicans, Allium cepa L. Var. Cepa, disc diffusion. Banda Aceh |
| id |
IOS3139.slims-13927 |
| institution |
Universitas Syiah Kuala |
| institution_id |
21 |
| institution_type |
library:university library |
| library |
Perpustakaan Universitas Syiah Kuala |
| library_id |
603 |
| collection |
ETD - Unsyiah |
| repository_id |
3139 |
| subject_area |
Karya Umum |
| city |
KOTA BANDA ACEH |
| province |
ACEH |
| repoId |
IOS3139 |
| first_indexed |
2016-09-15T18:49:03Z |
| last_indexed |
2016-09-24T07:10:49Z |
| recordtype |
dc |
| _version_ |
1680386247510458369 |
| score |
17.607244 |