Activity of antimalarial compounds from ethyl acetate fraction of sunflower leaves (Helianthus annuus L.) against Plasmodium falciparum parasites 3D7 strain
| Main Authors: | Mutiah, Roihatul, Badiah, Riadul, Hayati, Elok Kamilah |
|---|---|
| Format: | Journal PeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
Asian Pharma Press
, 2017
|
| Subjects: | |
| Online Access: |
http://repository.uin-malang.ac.id/1992/2/1992.pdf http://repository.uin-malang.ac.id/1992/ http://ajptonline.com/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Pharmacy%20and%20Technology;PID=2017-7-2-7 |
| ctrlnum |
1992 |
|---|---|
| fullrecord |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>http://repository.uin-malang.ac.id/1992/</relation><title>Activity of antimalarial compounds from ethyl acetate fraction of sunflower leaves (Helianthus annuus L.) against Plasmodium falciparum parasites 3D7 strain</title><creator>Mutiah, Roihatul</creator><creator>Badiah, Riadul</creator><creator>Hayati, Elok Kamilah</creator><subject>110101 Medical Biochemistry - Amino Acids and Metabolites</subject><description>Antimalarial study using methanol extract and ethyl acetate fraction of sunflower leaves had been done. The study was conducted to know antimalarial activity between methanol extract and ethyl acetate fraction at Plasmodium falciparum parasites 3D7 strain. Separation of compounds was done by maceration using methanol and partition using ethyl acetate. Identification of ethyl acetate fraction was done by using UPLC-MS instrument. The results shown ethyl acetate fraction obtained the highest peak based on database were artemisinin, heliangolide, linolenic acid, linoleic acid eupalinolide C. The results of antimalarial study shown that methanol extract had IC50 22.18 mg / mL, and ethyl acetate fraction had IC50 16.68 mg / mL. Antimalarial activity between methanol extract and ethyl acetate fraction showed no significant difference.</description><publisher>Asian Pharma Press</publisher><date>2017-04</date><type>Journal:Journal</type><type>PeerReview:PeerReviewed</type><type>Book:Book</type><language>eng</language><identifier>http://repository.uin-malang.ac.id/1992/2/1992.pdf</identifier><identifier> Mutiah, Roihatul and Badiah, Riadul and Hayati, Elok Kamilah (2017) Activity of antimalarial compounds from ethyl acetate fraction of sunflower leaves (Helianthus annuus L.) against Plasmodium falciparum parasites 3D7 strain. Asian Journal of Pharmacy and Technology, 7 (2). pp. 86-90. ISSN 2231-5713 </identifier><relation>http://ajptonline.com/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Pharmacy%20and%20Technology;PID=2017-7-2-7</relation><relation>10.5958/2231-5713.2017.00015.0</relation><recordID>1992</recordID></dc>
|
| language |
eng |
| format |
Journal:Journal Journal PeerReview:PeerReviewed PeerReview Book:Book Book |
| author |
Mutiah, Roihatul Badiah, Riadul Hayati, Elok Kamilah |
| title |
Activity of antimalarial compounds from ethyl acetate fraction of sunflower leaves (Helianthus annuus L.) against Plasmodium falciparum parasites 3D7 strain |
| publisher |
Asian Pharma Press |
| publishDate |
2017 |
| topic |
110101 Medical Biochemistry - Amino Acids and Metabolites |
| url |
http://repository.uin-malang.ac.id/1992/2/1992.pdf http://repository.uin-malang.ac.id/1992/ http://ajptonline.com/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Pharmacy%20and%20Technology;PID=2017-7-2-7 |
| contents |
Antimalarial study using methanol extract and ethyl acetate fraction of sunflower leaves had been done. The study was conducted to know antimalarial activity between methanol extract and ethyl acetate fraction at Plasmodium falciparum parasites 3D7 strain. Separation of compounds was done by maceration using methanol and partition using ethyl acetate. Identification of ethyl acetate fraction was done by using UPLC-MS instrument. The results shown ethyl acetate fraction obtained the highest peak based on database were artemisinin, heliangolide, linolenic acid, linoleic acid eupalinolide C. The results of antimalarial study shown that methanol extract had IC50 22.18 mg / mL, and ethyl acetate fraction had IC50 16.68 mg / mL. Antimalarial activity between methanol extract and ethyl acetate fraction showed no significant difference. |
| id |
IOS3710.1992 |
| institution |
Universitas Islam Negeri Maulana Malik Ibrahim Malang |
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onesearch.perpusnas.go.id mill.onesearch.id fkp2tn.onesearch.id ptki.onesearch.id |
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114 |
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library:university library |
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Perpustakaan UIN Maulana Malik Ibrahim Malang |
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504 |
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Research Repository UIN Maulana Malik Ibrahim Malang |
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3710 |
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Engineering/Ilmu Teknik Islam and Social Sciences/Islam dan Ilmu-ilmu Sosial |
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MALANG |
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JAWA TIMUR |
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IOS3710 |
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2017-08-20T01:56:08Z |
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2022-10-21T08:09:33Z |
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