Cover Image

PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG

Main Author: Hidayati, Nurul
Other Authors: AKADEMI FARMASI SAMARINDA
Format: Article info application/pdf Journal
Bahasa: eng
Terbitan: Akademi Farmasi Samarinda , 2017
Subjects:
Farmasi
Erythromycin
Staphylococcus aureus ATCC 25923
hydrolysis
dry syrup
suspension
photolysis
package
expose
Online Access: http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43
http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43/41
ctrlnum article-43
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG</title><creator>Hidayati, Nurul</creator><subject lang="en-US">Farmasi</subject><subject lang="en-US">Erythromycin, Staphylococcus aureus ATCC 25923, hydrolysis, dry syrup, suspension, photolysis, package, expose</subject><description lang="en-US">Erythromycin is a type of antibiotic medication. The drug is unstable when in the water because it can undergo hydrolysis process. Fortunately, it can be prevented by making dry syrup dosage form. In addition to hydrolysis, erythromycin can also have photolysis. For preventing the reaction, it can be done by packing the medication in an opaque and tightly closed container. This research was conducted to determine the effect of packaging on the stability of erythromycin suspension that has been exposed to direct sunlight within a period. The research was done by exposing erythromycin suspension, which was packed with three kinds of color packaging namely brown, translucent, and opaque, for 30 minutes, 60 minutes, 90 minutes and 120 minutes, then continued by a microbiological test with a diffusion method to determine the activity of erythromycin against Staphylococcus Aureus. The results of the research showed the existence of diameter of barrier areas around the spots that were given a test solution. It means that the test solution has antibiotic activity against bacteria. Preparations packaged in brown color have higher inhibition when compared with the opaque and translucent. It shows that the erythromycin suspension packaged in brown colors was more efficient in stabilizing the preparation</description><publisher lang="en-US">Akademi Farmasi Samarinda</publisher><contributor lang="en-US">AKADEMI FARMASI SAMARINDA</contributor><date>2017-01-26</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43</identifier><source lang="id-ID">Jurnal Ilmiah Manuntung; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 32-38</source><source lang="en-US">Jurnal Ilmiah Manuntung; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 32-38</source><language>eng</language><relation>http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43/41</relation><rights lang="en-US">Copyright (c) 2017 Jurnal Ilmiah Manuntung</rights><recordID>article-43</recordID></dc>
language eng
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
Other
File:application/pdf
File
Journal:Journal
author Hidayati, Nurul
author2 AKADEMI FARMASI SAMARINDA
title PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG
publisher Akademi Farmasi Samarinda
publishDate 2017
topic Farmasi
Erythromycin
Staphylococcus aureus ATCC 25923
hydrolysis
dry syrup
suspension
photolysis
package
expose
url http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43
http://jurnal.akfarsam.ac.id/index.php/jim_akfarsam/article/view/43/41
contents Erythromycin is a type of antibiotic medication. The drug is unstable when in the water because it can undergo hydrolysis process. Fortunately, it can be prevented by making dry syrup dosage form. In addition to hydrolysis, erythromycin can also have photolysis. For preventing the reaction, it can be done by packing the medication in an opaque and tightly closed container. This research was conducted to determine the effect of packaging on the stability of erythromycin suspension that has been exposed to direct sunlight within a period. The research was done by exposing erythromycin suspension, which was packed with three kinds of color packaging namely brown, translucent, and opaque, for 30 minutes, 60 minutes, 90 minutes and 120 minutes, then continued by a microbiological test with a diffusion method to determine the activity of erythromycin against Staphylococcus Aureus. The results of the research showed the existence of diameter of barrier areas around the spots that were given a test solution. It means that the test solution has antibiotic activity against bacteria. Preparations packaged in brown color have higher inhibition when compared with the opaque and translucent. It shows that the erythromycin suspension packaged in brown colors was more efficient in stabilizing the preparation
id IOS4057.article-43
institution Akademi Farmasi Samarinda
institution_id 769
institution_type library:university
library
library Perpustakaan AKADEMI FARMASI SAMARINDA
library_id 797
collection Jurnal Ilmiah Manuntung - Sains Farmasi dan Kesehatan
repository_id 4057
subject_area Medicine and Health/Ilmu Kedokteran, Ilmu Pengobatan dan Ilmu Kesehatan
Practical Pharmacy/Farmasi Praktis
city KOTA SAMARINDA
province KALIMANTAN TIMUR
shared_to_ipusnas_str 1
repoId IOS4057
first_indexed 2017-03-15T12:45:11Z
last_indexed 2017-07-11T05:31:45Z
recordtype dc
_version_ 1686082455722786816
score 17.610611

Lihat Juga