FRAKSI ETANOL 96% BIJI KORO BENGUK (Mucuna pruriens L.) SEBAGAI PENINGKAT KUALITAS SPERMATOZOA MENCIT (Mus musculus)
| Main Authors: | Winarni, Sri; Fakultas Kesehatan Masyarakat Universitas Diponegoro, Judiwati, Rina; Fakultas Kedokteran Universitas Airlangga, Prajogo, Bambang; Fakultas Farmasi Universitas Airlangga, Hayati, Alfiah; Fakultas Sains dan Teknologi Universitas Airlangga |
|---|---|
| Other Authors: | BADAN LITBANGKES KEMENKES |
| Format: | Article application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Pusat Teknologi Intervensi Kesehatan Masyarakat
, 2012
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| Online Access: |
http://ejournal.litbang.depkes.go.id/index.php/kespro/article/view/1345 |
| ctrlnum |
article-1345 |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="id-ID">FRAKSI ETANOL 96% BIJI KORO BENGUK (Mucuna pruriens L.) SEBAGAI PENINGKAT KUALITAS SPERMATOZOA MENCIT (Mus musculus)</title><creator>Winarni, Sri; Fakultas Kesehatan Masyarakat Universitas Diponegoro</creator><creator>Judiwati, Rina; Fakultas Kedokteran Universitas Airlangga</creator><creator>Prajogo, Bambang; Fakultas Farmasi Universitas Airlangga</creator><creator>Hayati, Alfiah; Fakultas Sains dan Teknologi Universitas Airlangga</creator><description lang="id-ID">Background: The examination of sperm quality is the main priority for infertility diagnosis. Based on previous study with mice, active ingredient of Mucuna pruriens L. or koro benguk (Papilionaceae), the L-dopa, may affect the quality of spermatozoa.Objective: Research was to study the effect of 96% ethanol fraction Mucuna pruriens seed on spermatozoaquality of mice exposed to 2-Methoxy ethanol. L-dopa in 96% ethanol fraction of M. pruriens seed was 14.7%.Methode: This was an experimental study using complete randomized design. Subjects were BALB/C mice (Mus musculus). Five groups served as control, 3 groups received subcutaneos injection of 2-ME as muchas 100 mg/kg.bw/day for 12 days, followed with 96% ethanol fraction Mucuna pruriens seed starting from14 mg/kg.bw/day, 28 mg/kg.bw/day, and 56 mg/kg.bw/day for 51 days.Result: The 96% ethanol fraction of Mucuna pruriens seeds are significant increase motility (p&lt;0,01) andthe percentage of normal spermatozoa morphology (p= 0,042).Conclusion: 96% ethanol fraction of Mucuna pruriens seeds are able to increase motility and the percentage of normal spermatozoa morphology in mice exposed to 2-ME. Keywords: Mucuna pruriens L., L-dopa, mouse spermatozoa</description><publisher lang="en-US">Pusat Teknologi Intervensi Kesehatan Masyarakat</publisher><contributor lang="id-ID">BADAN LITBANGKES KEMENKES</contributor><date>2012-11-04</date><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://ejournal.litbang.depkes.go.id/index.php/kespro/article/view/1345</identifier><source lang="id-ID">Jurnal Kesehatan Reproduksi; Vol 1, No 2 Apr (2011): Jurnal Kesehatan Reproduksi Vol. 1 No. 2 Tahun 2011; 60-66</source><source lang="en-US">Jurnal Kesehatan Reproduksi; Vol 1, No 2 Apr (2011): Jurnal Kesehatan Reproduksi Vol. 1 No. 2 Tahun 2011; 60-66</source><language>ind</language><rights>Authors who publish with Jurnal Kesehatan Reproduksi (Journal of Reproductive Health) agree to the following terms:Authors retain copyright and grant Jurnal Kesehatan Reproduksi right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Kesehatan Reproduksi (Journal of Reproductive Health).Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Kesehatan Reproduksi (Journal of Reproductive Health).</rights><recordID>article-1345</recordID></dc>
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ind |
| format |
Journal:Article Journal File:application/pdf File Journal:eJournal |
| author |
Winarni, Sri; Fakultas Kesehatan Masyarakat Universitas Diponegoro Judiwati, Rina; Fakultas Kedokteran Universitas Airlangga Prajogo, Bambang; Fakultas Farmasi Universitas Airlangga Hayati, Alfiah; Fakultas Sains dan Teknologi Universitas Airlangga |
| author2 |
BADAN LITBANGKES KEMENKES |
| title |
FRAKSI ETANOL 96% BIJI KORO BENGUK (Mucuna pruriens L.) SEBAGAI PENINGKAT KUALITAS SPERMATOZOA MENCIT (Mus musculus) |
| publisher |
Pusat Teknologi Intervensi Kesehatan Masyarakat |
| publishDate |
2012 |
| url |
http://ejournal.litbang.depkes.go.id/index.php/kespro/article/view/1345 |
| contents |
Background: The examination of sperm quality is the main priority for infertility diagnosis. Based on previous study with mice, active ingredient of Mucuna pruriens L. or koro benguk (Papilionaceae), the L-dopa, may affect the quality of spermatozoa.Objective: Research was to study the effect of 96% ethanol fraction Mucuna pruriens seed on spermatozoaquality of mice exposed to 2-Methoxy ethanol. L-dopa in 96% ethanol fraction of M. pruriens seed was 14.7%.Methode: This was an experimental study using complete randomized design. Subjects were BALB/C mice (Mus musculus). Five groups served as control, 3 groups received subcutaneos injection of 2-ME as muchas 100 mg/kg.bw/day for 12 days, followed with 96% ethanol fraction Mucuna pruriens seed starting from14 mg/kg.bw/day, 28 mg/kg.bw/day, and 56 mg/kg.bw/day for 51 days.Result: The 96% ethanol fraction of Mucuna pruriens seeds are significant increase motility (p<0,01) andthe percentage of normal spermatozoa morphology (p= 0,042).Conclusion: 96% ethanol fraction of Mucuna pruriens seeds are able to increase motility and the percentage of normal spermatozoa morphology in mice exposed to 2-ME. Keywords: Mucuna pruriens L., L-dopa, mouse spermatozoa |
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