Potential of Anti Breast Cancer Black Ethanol Rice Extract (Oryza sativa L). indica) In Decreasing Levels of CA 15-3 Serum in the White Mice Sprague dawley in Induction 7.12-Dimethylbenz (α) Antracene (DMBA) and Estrogen

Main Author: Abidin, Zanuar
Format: Article info application/pdf Journal
Bahasa: ind
Terbitan: Universitas Muhammadiyah Surabaya , 2017
Subjects:
Online Access: http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378
http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378/286
ctrlnum article-378
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="id-ID">Potential of Anti Breast Cancer Black Ethanol Rice Extract (Oryza sativa L). indica) In Decreasing Levels of CA 15-3 Serum in the White Mice Sprague dawley in Induction 7.12-Dimethylbenz (&#x3B1;) Antracene (DMBA) and Estrogen</title><creator>Abidin, Zanuar</creator><subject lang="id-ID">black rice, breast anticancer, CA 15-3 serum</subject><subject lang="id-ID">beras hitam,antikanker payudara,CA 15-3 serum</subject><description lang="id-ID">Breast cancer is cancer that has the high incidence in Indonesia. Black rice (Oryza sativa L. indica) is a plant that has an anticancer potency. This research aim is to prove black rice as a potential anticancer by using experimental animals, 20 Sprague Dawley female rats aged 7-8 weeks induced breast cancer by using the combination of 7,12-dimethylbenz (&#x3B1;) anthracene (DMBA) and estrogen. Rats were divided into two groups, namely the K-induced breast cancer and a group of P-induced cancer and treated with black rice. Black rice is given in the form of ethanol extract at a dose of 75 mg / kg / day for six weeks. Levels of CA 15-3 serum are used as a parameter. The result showed that the differences in levels of serum CA 15-3 are significant (p &lt;0.05). Serum CA 15-3 level in P group is lower than in K group. This study proved that the ethanol extract of black rice (Oryza sativa L. indica) has potential as an anticancer breast as indicated by decreased level of serum CA 15-3</description><publisher lang="en-US">Universitas Muhammadiyah Surabaya</publisher><contributor lang="id-ID"/><date>2017-01-27</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Journal:Article</type><type>File:application/pdf</type><identifier>http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378</identifier><identifier>10.30651/qm.v1i01.378</identifier><source lang="en-US">Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya; Vol 1, No 01 (2017)</source><source lang="id-ID">Qanun Medika - Jurnal FK UM Surabaya; Vol 1, No 01 (2017)</source><source>2548-9526</source><source>2541-2272</source><source>10.30651/qm.v1i01</source><language>ind</language><relation>http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378/286</relation><rights lang="en-US">Copyright (c) 2017 Qanun Medika - Jurnal FK UM Surabaya</rights><rights lang="en-US">http://creativecommons.org/licenses/by-nc-nd/4.0</rights><recordID>article-378</recordID></dc>
language ind
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
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File:application/pdf
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Journal:Journal
author Abidin, Zanuar
title Potential of Anti Breast Cancer Black Ethanol Rice Extract (Oryza sativa L). indica) In Decreasing Levels of CA 15-3 Serum in the White Mice Sprague dawley in Induction 7.12-Dimethylbenz (α) Antracene (DMBA) and Estrogen
publisher Universitas Muhammadiyah Surabaya
publishDate 2017
topic black rice
breast anticancer
CA 15-3 serum
beras hitam
antikanker payudara
url http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378
http://journal.um-surabaya.ac.id/index.php/qanunmedika/article/view/378/286
contents Breast cancer is cancer that has the high incidence in Indonesia. Black rice (Oryza sativa L. indica) is a plant that has an anticancer potency. This research aim is to prove black rice as a potential anticancer by using experimental animals, 20 Sprague Dawley female rats aged 7-8 weeks induced breast cancer by using the combination of 7,12-dimethylbenz (α) anthracene (DMBA) and estrogen. Rats were divided into two groups, namely the K-induced breast cancer and a group of P-induced cancer and treated with black rice. Black rice is given in the form of ethanol extract at a dose of 75 mg / kg / day for six weeks. Levels of CA 15-3 serum are used as a parameter. The result showed that the differences in levels of serum CA 15-3 are significant (p <0.05). Serum CA 15-3 level in P group is lower than in K group. This study proved that the ethanol extract of black rice (Oryza sativa L. indica) has potential as an anticancer breast as indicated by decreased level of serum CA 15-3
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