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Karakterisasi Senyawa Hasil Isolasi dari Ekstrak Etil Asetat Daun Namnam (Cynometra Cauliflora L.) yang Memiliki Aktivitas Antibakteri

Main Authors: Maharani, Tiah, Sukandar, Dede, Hermanto, Sandra
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Syarif Hidayatullah State Islamic University , 2016
Subjects:
Chemistry
antibacterial
disc diffusion
Namnam (Cynometracauliflora L.)
Online Access: http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084
http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084/pdf
ctrlnum article-3084
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">Karakterisasi Senyawa Hasil Isolasi dari Ekstrak Etil Asetat Daun Namnam (Cynometra Cauliflora L.) yang Memiliki Aktivitas Antibakteri</title><creator>Maharani, Tiah</creator><creator>Sukandar, Dede</creator><creator>Hermanto, Sandra</creator><subject lang="en-US">Chemistry</subject><subject lang="en-US">antibacterial; disc diffusion; Namnam (Cynometracauliflora L.)</subject><description lang="en-US">Namnam is known as a plant family of fabacea that contains phenolic compounds with diverse biological activities including antibacterial. The aim of this study was to isolate and characterize the antibacterial activity of compounds isolated from ethyl acetate extract of the leaves namanam (Cynometra cauliflora L.). Extraction was done by maceration, fractionation by column chromatography, antibacterial essay by disc diffusion method, and characterization of compounds with UV-Vis, FTIR spectroscopy and LCMS. Ethyl acetate extracts have antibacterial activity with inhibition zone respectively 12.25 and 6.00 mm to Escherecia coli and Stapilococcus aureus at a concentration of 100,000 ppm. The results of column chromatography fractions 23-30 yielded three isolates with Rf 0.20 cm; 0.33 cm and 0.87 cm. Characteristics of antibacterial active compounds in isolates 2 (Rf 0.33 cm) is based on the analysis results are UV-Vis absorption at &#x3BB;maks 206.93 nm, 268.40 nm, 328.58 nm, 383.98 nm and 386.98 nm , FTIR (KBr) showed -OH group 3415.68 cm-1, CH 2958.10 cm-1, C = C aromatic 1651.18 cm-1, C-OH cyclic 1019.88 cm-1 and CH aromatic 694.56 cm-1 and LCMS produce three main peak at a retention time of 4.82; 6.87 and 7.64 which is thought to be the compound 2-isopropyl-5-metilsikloheksil 2-hidroksipropanoat, Cuelure, and 2-[(2-Hydroxycyclohexyl) oxy] cyclohexanecarboxylate. &#xA0; Key word: antibacterial, disc diffusion, Namnam (Cynometracauliflora L.). DOI: http://dx.doi.org/10.15408/jkv.v2i1.3084</description><publisher lang="en-US">Syarif Hidayatullah State Islamic University</publisher><contributor lang="en-US"/><date>2016-05-31</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>Other:</type><type>Other:</type><type>File:application/pdf</type><identifier>http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084</identifier><identifier>10.15408/jkv.v2i1.3084</identifier><source lang="en-US">Jurnal Kimia Valensi; Jurnal Kimia VALENSI Volume 2, No. 1, Mei 2016; 55-62</source><source>2548-3013</source><source>2460-6065</source><language>eng</language><relation>http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084/pdf</relation><rights lang="en-US">Copyright (c) 2019 Tiah Maharani, Dede Sukandar, Sandra Hermanto</rights><rights lang="en-US">https://creativecommons.org/licenses/by-sa/4.0</rights><recordID>article-3084</recordID></dc>
language eng
format Journal:Article
Journal
Other:info:eu-repo/semantics/publishedVersion
Other
Other:
File:application/pdf
File
Journal:eJournal
author Maharani, Tiah
Sukandar, Dede
Hermanto, Sandra
title Karakterisasi Senyawa Hasil Isolasi dari Ekstrak Etil Asetat Daun Namnam (Cynometra Cauliflora L.) yang Memiliki Aktivitas Antibakteri
publisher Syarif Hidayatullah State Islamic University
publishDate 2016
topic Chemistry
antibacterial
disc diffusion
Namnam (Cynometracauliflora L.)
url http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084
http://journal.uinjkt.ac.id/index.php/valensi/article/view/3084/pdf
contents Namnam is known as a plant family of fabacea that contains phenolic compounds with diverse biological activities including antibacterial. The aim of this study was to isolate and characterize the antibacterial activity of compounds isolated from ethyl acetate extract of the leaves namanam (Cynometra cauliflora L.). Extraction was done by maceration, fractionation by column chromatography, antibacterial essay by disc diffusion method, and characterization of compounds with UV-Vis, FTIR spectroscopy and LCMS. Ethyl acetate extracts have antibacterial activity with inhibition zone respectively 12.25 and 6.00 mm to Escherecia coli and Stapilococcus aureus at a concentration of 100,000 ppm. The results of column chromatography fractions 23-30 yielded three isolates with Rf 0.20 cm; 0.33 cm and 0.87 cm. Characteristics of antibacterial active compounds in isolates 2 (Rf 0.33 cm) is based on the analysis results are UV-Vis absorption at λmaks 206.93 nm, 268.40 nm, 328.58 nm, 383.98 nm and 386.98 nm , FTIR (KBr) showed -OH group 3415.68 cm-1, CH 2958.10 cm-1, C = C aromatic 1651.18 cm-1, C-OH cyclic 1019.88 cm-1 and CH aromatic 694.56 cm-1 and LCMS produce three main peak at a retention time of 4.82; 6.87 and 7.64 which is thought to be the compound 2-isopropyl-5-metilsikloheksil 2-hidroksipropanoat, Cuelure, and 2-[(2-Hydroxycyclohexyl) oxy] cyclohexanecarboxylate. Key word: antibacterial, disc diffusion, Namnam (Cynometracauliflora L.). DOI: http://dx.doi.org/10.15408/jkv.v2i1.3084
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first_indexed 2016-11-12T12:13:12Z
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