EFEK PENURUNAN KADAR GULA DARAH SEWAKTU PASIEN DIABETES PENURUNAN KADAR GULA DARAH SEWAKTU PASIEN DIABETES DENGAN MENGGUNAKAN SUPLEMEN EKSTRAK PARE (Momordica charantia) BENTUK TABLET “SUGAR BALANCE"
Daftar Isi:
- Blood Glucose Lowering Effect in Type II Diabetes Mellitus Patients with Metformin Use Supplemented with Bitter Melon (Momordica Charatia) Extract in Tablet FormType II Diabetes Mellitus is a metabolic syndrome caused by insulin resistance. The first line treatment option most commonly used is Metformin, which has some side effects to gastrointestinal system. One of the alternative is bitter melon (Momordica Charantia) which contain a sterol glycoside compound called charantin that is able to improve insulin usage in type II diabetes patients. The purpose of this study is to observe the glucose lowering effects of bitter melon extract supplementation in type II diabetes patients with Metformin use.This study is an experimental study using the pre and posttest with one group design. The subject of this study, are comprised of type II diabetes patients who take metformin routinely with blood glucose lower than 300 mg/dL. The total amount of subject involved in this study is 60 patients which was chosen with purposive sampling that was divided in 2 separate period of observation. Blood glucose measurement was done in pretest, posttest, and during the observation period with a 2-day interval with each measurement.Supplement of single tablet (1700 mg) of bitter melon extract in 15-day period reduce the blood glucose in 33% od subjects while supplement of two tablet (3400 mg) of bitter melon extract shows a reduction of 63,6 to 91,9 mg/dl in blood sugar of subjects.Supplement of bitter melon extract during the 15-day observation period has a significant effect toward type II diabetes patients with routine metformin use.