ISOLASI METABOLIT SEKUNDER DARI JAMUR ENDOFITIK EKSTRASELULER DAUN MANGGIS (Garcinia mangostana) DAN AKTIVITAS ANTIOKSIDANNYA
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4110 |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>http://repository.unsri.ac.id/4110/</relation><title>ISOLASI METABOLIT SEKUNDER DARI JAMUR ENDOFITIK EKSTRASELULER DAUN MANGGIS (Garcinia mangostana) DAN AKTIVITAS ANTIOKSIDANNYA</title><creator>PUTRI, AYU</creator><creator>Elfita, Elfita</creator><creator>Muharni, Muharni</creator><subject>QD1-999 Chemistry</subject><subject>QD241-441 Organic chemistry</subject><subject>QD701-731 Photochemistry</subject><description>Six endophytic fungi from mangosteen leaf have been isolated and also screening antioxidant activity with DPPH method (1,1-Diphenyl-2-picryl-hydrazil). Extract endophytic fungi DM6 provides high antioxidant activity with IC50 13,21 μg / mL. Fungi DM6 proceeds to the isolation phase of its secondary metabolite. Endophytic fungi was cultivated in a 300 mL medium PDB (in 10 bottles), then incubated for 6 weeks at room temperature and in a static state. Extraction of extracellular secondary metabolite compounds was carried out partitionally, then evaporated and gravitational column chromatography. The results of pure compound isolation identified using UV, FT-IR, and NMR spectrophotometers. Structure of the compound endophytic fungi of mangosteen leaf is 6-(sec-butyl)-4-hydroxy-3-methyl-2H-pyran-2-one. Then, the pure compound isolation have antioxidant activity and gave IC50 461,13 μg / mL. These results suggest that the pure compound of endophytic fungi of mangosteen leaf is classified as inactive as an antioxidant because IC50> 100 μg /mL.</description><date>2018-06-07</date><type>Thesis:Thesis</type><type>PeerReview:NonPeerReviewed</type><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/1/RAMA_47201_08031281419054_0026036901_0004036903_01_front_ref.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/2/RAMA_47201_08031281419054_0026036901_0004036903_02.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/3/RAMA_47201_08031281419054_0026036901_0004036903_03.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/4/RAMA_47201_08031281419054_0026036901_0004036903_04.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/5/RAMA_47201_08031281419054_0026036901_0004036903_05.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/6/RAMA_47201_08031281419054_0026036901_0004036903_06_ref.pdf</identifier><type>Book:Book</type><language>ind</language><rights>cc_public_domain</rights><identifier>http://repository.unsri.ac.id/4110/7/RAMA_47201_08031281419054_0026036901_0004036903_07_lamp.pdf</identifier><identifier> PUTRI, AYU and Elfita, Elfita and Muharni, Muharni (2018) ISOLASI METABOLIT SEKUNDER DARI JAMUR ENDOFITIK EKSTRASELULER DAUN MANGGIS (Garcinia mangostana) DAN AKTIVITAS ANTIOKSIDANNYA. Undergraduate thesis, Sriwijaya University. </identifier><recordID>4110</recordID></dc>
|
| language |
ind |
| format |
Thesis:Thesis Thesis PeerReview:NonPeerReviewed PeerReview Book:Book Book |
| author |
PUTRI, AYU Elfita, Elfita Muharni, Muharni |
| title |
ISOLASI METABOLIT SEKUNDER DARI JAMUR ENDOFITIK EKSTRASELULER DAUN MANGGIS (Garcinia mangostana) DAN AKTIVITAS ANTIOKSIDANNYA |
| publishDate |
2018 |
| isbn |
0803128141905 |
| topic |
QD1-999 Chemistry QD241-441 Organic chemistry QD701-731 Photochemistry |
| url |
http://repository.unsri.ac.id/4110/1/RAMA_47201_08031281419054_0026036901_0004036903_01_front_ref.pdf http://repository.unsri.ac.id/4110/2/RAMA_47201_08031281419054_0026036901_0004036903_02.pdf http://repository.unsri.ac.id/4110/3/RAMA_47201_08031281419054_0026036901_0004036903_03.pdf http://repository.unsri.ac.id/4110/4/RAMA_47201_08031281419054_0026036901_0004036903_04.pdf http://repository.unsri.ac.id/4110/5/RAMA_47201_08031281419054_0026036901_0004036903_05.pdf http://repository.unsri.ac.id/4110/6/RAMA_47201_08031281419054_0026036901_0004036903_06_ref.pdf http://repository.unsri.ac.id/4110/7/RAMA_47201_08031281419054_0026036901_0004036903_07_lamp.pdf http://repository.unsri.ac.id/4110/ |
| contents |
Six endophytic fungi from mangosteen leaf have been isolated and also screening antioxidant activity with DPPH method (1,1-Diphenyl-2-picryl-hydrazil). Extract endophytic fungi DM6 provides high antioxidant activity with IC50 13,21 μg / mL. Fungi DM6 proceeds to the isolation phase of its secondary metabolite. Endophytic fungi was cultivated in a 300 mL medium PDB (in 10 bottles), then incubated for 6 weeks at room temperature and in a static state. Extraction of extracellular secondary metabolite compounds was carried out partitionally, then evaporated and gravitational column chromatography. The results of pure compound isolation identified using UV, FT-IR, and NMR spectrophotometers. Structure of the compound endophytic fungi of mangosteen leaf is 6-(sec-butyl)-4-hydroxy-3-methyl-2H-pyran-2-one. Then, the pure compound isolation have antioxidant activity and gave IC50 461,13 μg / mL. These results suggest that the pure compound of endophytic fungi of mangosteen leaf is classified as inactive as an antioxidant because IC50> 100 μg /mL. |
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IOS8119.4110 |
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Universitas Sriwijaya |
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177 |
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UPT Perpustakaan Universitas Sriwijaya |
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Sriwijaya University Institutional Repository |
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OGAN ILIR |
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SUMATERA SELATAN |
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1 |
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2020-03-23T07:55:33Z |
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2020-03-23T07:55:33Z |
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dc |
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17.60897 |