Molecular Interaction of Chili Compounds (Capsicum annum L) as a COX-2 Inhibitor
Main Authors: | Bare, Yohanes, AHmad, Nurul Imaniyah, Bunga, Yohanes Nong |
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Format: | Article info application/pdf |
Bahasa: | eng |
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Universitas Wiralodra
, 2022
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Subjects: | |
Online Access: |
https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124 https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124/83 |
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article-124 |
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<dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><title lang="en-US">Molecular Interaction of Chili Compounds (Capsicum annum L) as a COX-2 Inhibitor</title><creator>Bare, Yohanes</creator><creator>AHmad, Nurul Imaniyah</creator><creator>Bunga, Yohanes Nong</creator><subject lang="en-US">CO2X</subject><subject lang="en-US">Psyco-chemical</subject><subject lang="en-US">Red chili</subject><description lang="en-US">Curly red chili (Capsicum annum L.) is a vegetable that has health benefits. Besides being used as an addictive substance in traditional medicine, Capsicum annum L. is also used for cough treatment, antiseptic, anti-irritant, anti-inflammatory. This research study aims to analyze the physico-chemical and its molecular interactions with COX-2. Capsaicin (CID: 1548943), dihydrocapsaicin (CID: 107982) and homocapsaicin (CID: 6442566) compounds were downloaded from pubchem. While the COX protein (ID: 6cox) from the Protein Data Bank. Molecular interaction and analized by HEX. 8.0.0 and Discovery Studio. The three compounds contained in curly red chilies have unique physico-chemical characteristics. The results of the interaction show that the curly mera chili has a physiological function by inhibiting the performance of COX-2</description><publisher lang="en-US">Universitas Wiralodra</publisher><date>2022-01-31</date><type>Journal:Article</type><type>Other:info:eu-repo/semantics/publishedVersion</type><type>File:application/pdf</type><identifier>https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124</identifier><identifier>10.31943/mangiferaedu.v6i2.124</identifier><source lang="en-US">Mangifera Edu; Vol 6 No 2 (2022): Jurnal Mangifera Edu; 115-128</source><source lang="id-ID">Mangifera Edu; Vol 6 No 2 (2022): Jurnal Mangifera Edu; 115-128</source><source>2622-3384</source><source>2527-9939</source><source>10.31943/mangiferaedu.v6i2</source><language>eng</language><relation>https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124/83</relation><rights lang="en-US">Copyright (c) 2022 Mangifera Edu</rights><recordID>article-124</recordID></dc>
|
language |
eng |
format |
Journal:Article Journal Other:info:eu-repo/semantics/publishedVersion Other File:application/pdf File |
author |
Bare, Yohanes AHmad, Nurul Imaniyah Bunga, Yohanes Nong |
title |
Molecular Interaction of Chili Compounds (Capsicum annum L) as a COX-2 Inhibitor |
publisher |
Universitas Wiralodra |
publishDate |
2022 |
topic |
CO2X Psyco-chemical Red chili |
url |
https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124 https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124/83 |
contents |
Curly red chili (Capsicum annum L.) is a vegetable that has health benefits. Besides being used as an addictive substance in traditional medicine, Capsicum annum L. is also used for cough treatment, antiseptic, anti-irritant, anti-inflammatory. This research study aims to analyze the physico-chemical and its molecular interactions with COX-2. Capsaicin (CID: 1548943), dihydrocapsaicin (CID: 107982) and homocapsaicin (CID: 6442566) compounds were downloaded from pubchem. While the COX protein (ID: 6cox) from the Protein Data Bank. Molecular interaction and analized by HEX. 8.0.0 and Discovery Studio. The three compounds contained in curly red chilies have unique physico-chemical characteristics. The results of the interaction show that the curly mera chili has a physiological function by inhibiting the performance of COX-2 |
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JAWA BARAT |
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