Molecular Interaction of Chili Compounds (Capsicum annum L) as a COX-2 Inhibitor
| Main Authors: | Bare, Yohanes, AHmad, Nurul Imaniyah, Bunga, Yohanes Nong |
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| Format: | Article info application/pdf |
| Bahasa: | eng |
| Terbitan: |
Universitas Wiralodra
, 2022
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| Subjects: | |
| Online Access: |
https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124 https://jurnal.biounwir.ac.id/index.php/mangiferaedu/article/view/124/83 |
Daftar Isi:
- Curly red chili (Capsicum annum L.) is a vegetable that has health benefits. Besides being used as an addictive substance in traditional medicine, Capsicum annum L. is also used for cough treatment, antiseptic, anti-irritant, anti-inflammatory. This research study aims to analyze the physico-chemical and its molecular interactions with COX-2. Capsaicin (CID: 1548943), dihydrocapsaicin (CID: 107982) and homocapsaicin (CID: 6442566) compounds were downloaded from pubchem. While the COX protein (ID: 6cox) from the Protein Data Bank. Molecular interaction and analized by HEX. 8.0.0 and Discovery Studio. The three compounds contained in curly red chilies have unique physico-chemical characteristics. The results of the interaction show that the curly mera chili has a physiological function by inhibiting the performance of COX-2